LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1235 1018 4405 0.2289 -0.1232
MDA-MB-231 HG-6-64-01
10
uM
LJP6
 72
hr
 1235 234 4405 0.0524 -0.6111
MDA-MB-231 Neratinib
0.04
uM
LJP5
 72
hr
 1235 4700 4660 1.0099 1.0111
MDA-MB-231 Neratinib
0.12
uM
LJP5
 72
hr
 1235 4531 4660 0.9743 0.9739
MDA-MB-231 Neratinib
0.37
uM
LJP5
 72
hr
 1235 3537 4660 0.7596 0.7325
MDA-MB-231 Neratinib
1.11
uM
LJP5
 72
hr
 1235 2421 4660 0.5183 0.4159
MDA-MB-231 Neratinib
3.33
uM
LJP5
 72
hr
 1235 1539 4660 0.3309 0.1218
MDA-MB-231 Neratinib
10
uM
LJP5
 72
hr
 1235 797 4660 0.1734 -0.2107
MDA-MB-231 JW-7-24-1
0.04
uM
LJP6
 72
hr
 1235 4157 4405 0.9428 0.9355
MDA-MB-231 JW-7-24-1
0.12
uM
LJP6
 72
hr
 1235 4098 4405 0.9292 0.9199
MDA-MB-231 JW-7-24-1
0.37
uM
LJP6
 72
hr
 1235 3542 4405 0.8028 0.7723
MDA-MB-231 JW-7-24-1
1.11
uM
LJP6
 72
hr
 1235 2889 4405 0.6546 0.5850
MDA-MB-231 JW-7-24-1
3.33
uM
LJP6
 72
hr
 1235 2617 4405 0.5934 0.5030
MDA-MB-231 JW-7-24-1
10
uM
LJP6
 72
hr
 1235 632 4405 0.1429 -0.3106
MDA-MB-231 Dasatinib
0.04
uM
LJP5
 72
hr
 1235 2691 4660 0.5783 0.5023
MDA-MB-231 Dasatinib
0.04
uM
LJP6
 72
hr
 1235 807 4405 0.1832 -0.2078
MDA-MB-231 Dasatinib
0.12
uM
LJP5
 72
hr
 1235 1345 4660 0.2890 0.0451
MDA-MB-231 Dasatinib
0.12
uM
LJP6
 72
hr
 1235 801 4405 0.1820 -0.2107
MDA-MB-231 Dasatinib
0.37
uM
LJP5
 72
hr
 1235 790 4660 0.1696 -0.2095
MDA-MB-231 Dasatinib
0.37
uM
LJP6
 72
hr
 1235 771 4405 0.1752 -0.2270
MDA-MB-231 Dasatinib
1.11
uM
LJP5
 72
hr
 1235 653 4660 0.1398 -0.2854
MDA-MB-231 Dasatinib
1.11
uM
LJP6
 72
hr
 1235 661 4405 0.1498 -0.2930
MDA-MB-231 Dasatinib
3.33
uM
LJP5
 72
hr
 1235 671 4660 0.1440 -0.2738
MDA-MB-231 Dasatinib
3.33
uM
LJP6
 72
hr
 1235 627 4405 0.1421 -0.3156
MDA-MB-231 Dasatinib
10
uM
LJP5
 72
hr
 1235 638 4660 0.1362 -0.2971