LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Omipalisib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 1362 | 4168 | 0.3269 | -0.0182 |
| SK-BR-3 | Omipalisib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 1277 | 4168 | 0.3064 | -0.0578 |
| SK-BR-3 | Omipalisib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 1126 | 4168 | 0.2700 | -0.1306 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 924 | 4168 | 0.2214 | -0.2343 |
| SK-BR-3 | Omipalisib | 10 | uM | LJP6 | 72 | hr | 1401 | 855 | 4168 | 0.2050 | -0.2702 |
| SK-BR-3 | Buparlisib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3630 | 4245 | 0.8570 | 0.8164 |
| SK-BR-3 | Buparlisib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 2767 | 4245 | 0.6535 | 0.5326 |
| SK-BR-3 | Buparlisib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 1895 | 4245 | 0.4470 | 0.2069 |
| SK-BR-3 | Buparlisib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 1278 | 4245 | 0.3015 | -0.0575 |
| SK-BR-3 | Buparlisib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 1053 | 4245 | 0.2477 | -0.1666 |
| SK-BR-3 | Buparlisib | 10 | uM | LJP5 | 72 | hr | 1401 | 978 | 4245 | 0.2309 | -0.2025 |
| SK-BR-3 | XL147 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4661 | 4245 | 1.0997 | 1.1246 |
| SK-BR-3 | XL147 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4821 | 4245 | 1.1409 | 1.1763 |
| SK-BR-3 | XL147 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4686 | 4245 | 1.1119 | 1.1421 |
| SK-BR-3 | XL147 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4944 | 4245 | 1.1686 | 1.2092 |
| SK-BR-3 | XL147 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4818 | 4245 | 1.1412 | 1.1776 |
| SK-BR-3 | XL147 | 10 | uM | LJP5 | 72 | hr | 1401 | 3703 | 4245 | 0.8749 | 0.8411 |
| SK-BR-3 | Y39983 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4244 | 4168 | 1.0176 | 1.0213 |
| SK-BR-3 | Y39983 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4181 | 4168 | 1.0031 | 1.0041 |
| SK-BR-3 | Y39983 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 3927 | 4168 | 0.9422 | 0.9251 |
| SK-BR-3 | Y39983 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3731 | 4168 | 0.8948 | 0.8631 |
| SK-BR-3 | Y39983 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 3318 | 4168 | 0.7959 | 0.7294 |
| SK-BR-3 | Y39983 | 10 | uM | LJP6 | 72 | hr | 1401 | 1540 | 4168 | 0.3693 | 0.0606 |
| SK-BR-3 | Nintedanib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4432 | 4168 | 1.0627 | 1.0782 |
| SK-BR-3 | Nintedanib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4054 | 4168 | 0.9726 | 0.9649 |