LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 CGP60474
1.11
uM
LJP5
 72
hr
 1235 407 4660 0.0875 -0.4405
MDA-MB-231 CGP60474
1.11
uM
LJP6
 72
hr
 1235 344 4405 0.0776 -0.5060
MDA-MB-231 CGP60474
3.33
uM
LJP5
 72
hr
 1235 448 4660 0.0962 -0.4119
MDA-MB-231 CGP60474
3.33
uM
LJP6
 72
hr
 1235 292 4405 0.0657 -0.5526
MDA-MB-231 CGP60474
10
uM
LJP5
 72
hr
 1235 454 4660 0.0971 -0.4095
MDA-MB-231 CGP60474
10
uM
LJP6
 72
hr
 1235 340 4405 0.0765 -0.5175
MDA-MB-231 PD173074
0.04
uM
LJP6
 72
hr
 1235 4661 4405 1.0586 1.0633
MDA-MB-231 PD173074
0.12
uM
LJP6
 72
hr
 1235 4694 4405 1.0666 1.0721
MDA-MB-231 PD173074
0.37
uM
LJP6
 72
hr
 1235 5078 4405 1.1552 1.1644
MDA-MB-231 PD173074
1.11
uM
LJP6
 72
hr
 1235 4916 4405 1.1188 1.1268
MDA-MB-231 PD173074
3.33
uM
LJP6
 72
hr
 1235 4648 4405 1.0568 1.0618
MDA-MB-231 PD173074
10
uM
LJP6
 72
hr
 1235 1624 4405 0.3683 0.1566
MDA-MB-231 Crizotinib
0.04
uM
LJP5
 72
hr
 1235 4502 4660 0.9666 0.9652
MDA-MB-231 Crizotinib
0.12
uM
LJP5
 72
hr
 1235 4475 4660 0.9617 0.9604
MDA-MB-231 Crizotinib
0.37
uM
LJP5
 72
hr
 1235 4053 4660 0.8712 0.8616
MDA-MB-231 Crizotinib
1.11
uM
LJP5
 72
hr
 1235 2201 4660 0.4727 0.3516
MDA-MB-231 Crizotinib
3.33
uM
LJP5
 72
hr
 1235 1421 4660 0.3055 0.0758
MDA-MB-231 Crizotinib
10
uM
LJP5
 72
hr
 1235 939 4660 0.2016 -0.1342
MDA-MB-231 BMS345541
0.04
uM
LJP6
 72
hr
 1235 4330 4405 0.9836 0.9824
MDA-MB-231 BMS345541
0.12
uM
LJP6
 72
hr
 1235 3792 4405 0.8593 0.8389
MDA-MB-231 BMS345541
0.37
uM
LJP6
 72
hr
 1235 3687 4405 0.8374 0.8156
MDA-MB-231 BMS345541
1.11
uM
LJP6
 72
hr
 1235 2848 4405 0.6458 0.5744
MDA-MB-231 BMS345541
3.33
uM
LJP6
 72
hr
 1235 1832 4405 0.4155 0.2380
MDA-MB-231 BMS345541
10
uM
LJP6
 72
hr
 1235 408 4405 0.0926 -0.4547
MDA-MB-231 KIN001-043
0.04
uM
LJP6
 72
hr
 1235 3783 4405 0.8578 0.8381