LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 KIN001-043
0.12
uM
LJP6
 72
hr
 1235 3477 4405 0.7895 0.7573
MDA-MB-231 KIN001-043
0.37
uM
LJP6
 72
hr
 1235 3573 4405 0.8116 0.7846
MDA-MB-231 KIN001-043
1.11
uM
LJP6
 72
hr
 1235 3327 4405 0.7554 0.7160
MDA-MB-231 KIN001-043
3.33
uM
LJP6
 72
hr
 1235 3354 4405 0.7610 0.7224
MDA-MB-231 KIN001-043
10
uM
LJP6
 72
hr
 1235 1167 4405 0.2641 -0.0364
MDA-MB-231 Saracatinib
0.04
uM
LJP6
 72
hr
 1235 3593 4405 0.8158 0.7898
MDA-MB-231 Saracatinib
0.12
uM
LJP6
 72
hr
 1235 3260 4405 0.7402 0.6970
MDA-MB-231 Saracatinib
0.37
uM
LJP6
 72
hr
 1235 2933 4405 0.6652 0.6001
MDA-MB-231 Saracatinib
1.11
uM
LJP6
 72
hr
 1235 2835 4405 0.6440 0.5730
MDA-MB-231 Saracatinib
3.33
uM
LJP6
 72
hr
 1235 2626 4405 0.5955 0.5063
MDA-MB-231 Saracatinib
10
uM
LJP6
 72
hr
 1235 2083 4405 0.4719 0.3257
MDA-MB-231 Sigma A6730
0.04
uM
LJP5
 72
hr
 1235 4511 4660 0.9692 0.9682
MDA-MB-231 Sigma A6730
0.12
uM
LJP5
 72
hr
 1235 4466 4660 0.9596 0.9581
MDA-MB-231 Sigma A6730
0.37
uM
LJP5
 72
hr
 1235 4453 4660 0.9565 0.9547
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 1235 4267 4660 0.9169 0.9120
MDA-MB-231 Sigma A6730
3.33
uM
LJP5
 72
hr
 1235 4244 4660 0.9122 0.9069
MDA-MB-231 Sigma A6730
10
uM
LJP5
 72
hr
 1235 2695 4660 0.5793 0.5024
MDA-MB-231 WH-4-025
0.04
uM
LJP5
 72
hr
 1235 3774 4660 0.8091 0.7891
MDA-MB-231 WH-4-025
0.12
uM
LJP5
 72
hr
 1235 3320 4660 0.7109 0.6716
MDA-MB-231 WH-4-025
0.37
uM
LJP5
 72
hr
 1235 1296 4660 0.2784 0.0244
MDA-MB-231 WH-4-025
1.11
uM
LJP5
 72
hr
 1235 861 4660 0.1845 -0.1736
MDA-MB-231 WH-4-025
3.33
uM
LJP5
 72
hr
 1235 880 4660 0.1891 -0.1628
MDA-MB-231 WH-4-025
10
uM
LJP5
 72
hr
 1235 420 4660 0.0906 -0.4310
MDA-MB-231 R406
0.04
uM
LJP6
 72
hr
 1235 4461 4405 1.0126 1.0129
MDA-MB-231 R406
0.12
uM
LJP6
 72
hr
 1235 4308 4405 0.9787 0.9771