LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 R406
0.37
uM
LJP6
 72
hr
 1235 4314 4405 0.9795 0.9768
MDA-MB-231 R406
1.11
uM
LJP6
 72
hr
 1235 4000 4405 0.9072 0.8937
MDA-MB-231 R406
3.33
uM
LJP6
 72
hr
 1235 3183 4405 0.7224 0.6725
MDA-MB-231 R406
10
uM
LJP6
 72
hr
 1235 1315 4405 0.2992 0.0343
MDA-MB-231 BI-2536
0.04
uM
LJP6
 72
hr
 1235 999 4405 0.2264 -0.1114
MDA-MB-231 BI-2536
0.12
uM
LJP6
 72
hr
 1235 1054 4405 0.2392 -0.0838
MDA-MB-231 BI-2536
0.37
uM
LJP6
 72
hr
 1235 1015 4405 0.2302 -0.1033
MDA-MB-231 BI-2536
1.11
uM
LJP6
 72
hr
 1235 1035 4405 0.2346 -0.0940
MDA-MB-231 BI-2536
3.33
uM
LJP6
 72
hr
 1235 1091 4405 0.2472 -0.0684
MDA-MB-231 BI-2536
10
uM
LJP6
 72
hr
 1235 617 4405 0.1398 -0.3171
MDA-MB-231 A443654
0.04
uM
LJP6
 72
hr
 1235 3529 4405 0.8022 0.7738
MDA-MB-231 A443654
0.12
uM
LJP6
 72
hr
 1235 2124 4405 0.4821 0.3429
MDA-MB-231 A443654
0.37
uM
LJP6
 72
hr
 1235 726 4405 0.1648 -0.2526
MDA-MB-231 A443654
1.11
uM
LJP6
 72
hr
 1235 525 4405 0.1199 -0.3748
MDA-MB-231 A443654
3.33
uM
LJP6
 72
hr
 1235 414 4405 0.0940 -0.4497
MDA-MB-231 A443654
10
uM
LJP6
 72
hr
 1235 344 4405 0.0782 -0.5024
MDA-MB-231 SB590885
0.04
uM
LJP5
 72
hr
 1235 4598 4660 0.9853 0.9832
MDA-MB-231 SB590885
0.12
uM
LJP5
 72
hr
 1235 4334 4660 0.9287 0.9228
MDA-MB-231 SB590885
0.37
uM
LJP5
 72
hr
 1235 4197 4660 0.8997 0.8918
MDA-MB-231 SB590885
1.11
uM
LJP5
 72
hr
 1235 4217 4660 0.9041 0.8967
MDA-MB-231 SB590885
3.33
uM
LJP5
 72
hr
 1235 3806 4660 0.8153 0.7959
MDA-MB-231 SB590885
10
uM
LJP5
 72
hr
 1235 280 4660 0.0601 -0.5400
MDA-MB-231 Pictilisib
0.04
uM
LJP6
 72
hr
 1235 3867 4405 0.8776 0.8620
MDA-MB-231 Pictilisib
0.12
uM
LJP6
 72
hr
 1235 3713 4405 0.8428 0.8216
MDA-MB-231 Pictilisib
0.37
uM
LJP6
 72
hr
 1235 3275 4405 0.7442 0.7021