LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | GSK1059615 | 10 | uM | LJP5 | 72 | hr | 1401 | 861 | 4245 | 0.1997 | -0.2786 |
| SK-BR-3 | GSK1059615 | 10 | uM | LJP6 | 72 | hr | 1401 | 694 | 4168 | 0.1664 | -0.3642 |
| SK-BR-3 | Brivanib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4177 | 4245 | 0.9804 | 0.9706 |
| SK-BR-3 | Brivanib | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4164 | 4245 | 0.9817 | 0.9780 |
| SK-BR-3 | Brivanib | 0.37 | uM | LJP5 | 72 | hr | 1401 | 4205 | 4245 | 0.9885 | 0.9831 |
| SK-BR-3 | Brivanib | 1.11 | uM | LJP5 | 72 | hr | 1401 | 4209 | 4245 | 0.9894 | 0.9841 |
| SK-BR-3 | Brivanib | 3.33 | uM | LJP5 | 72 | hr | 1401 | 4138 | 4245 | 0.9744 | 0.9674 |
| SK-BR-3 | Brivanib | 10 | uM | LJP5 | 72 | hr | 1401 | 4050 | 4245 | 0.9525 | 0.9381 |
| SK-BR-3 | CHIR-99021 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3730 | 4168 | 0.8962 | 0.8651 |
| SK-BR-3 | CHIR-99021 | 0.12 | uM | LJP6 | 72 | hr | 1401 | 3900 | 4168 | 0.9355 | 0.9168 |
| SK-BR-3 | CHIR-99021 | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4056 | 4168 | 0.9734 | 0.9663 |
| SK-BR-3 | CHIR-99021 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 3966 | 4168 | 0.9516 | 0.9381 |
| SK-BR-3 | CHIR-99021 | 3.33 | uM | LJP6 | 72 | hr | 1401 | 4000 | 4168 | 0.9607 | 0.9498 |
| SK-BR-3 | CHIR-99021 | 10 | uM | LJP6 | 72 | hr | 1401 | 3218 | 4168 | 0.7723 | 0.6970 |
| SK-BR-3 | Linifanib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4563 | 4168 | 1.0943 | 1.1173 |
| SK-BR-3 | Linifanib | 0.12 | uM | LJP6 | 72 | hr | 1401 | 4479 | 4168 | 1.0738 | 1.0912 |
| SK-BR-3 | Linifanib | 0.37 | uM | LJP6 | 72 | hr | 1401 | 4681 | 4168 | 1.1232 | 1.1535 |
| SK-BR-3 | Linifanib | 1.11 | uM | LJP6 | 72 | hr | 1401 | 4424 | 4168 | 1.0606 | 1.0753 |
| SK-BR-3 | Linifanib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 4468 | 4168 | 1.0721 | 1.0908 |
| SK-BR-3 | Linifanib | 10 | uM | LJP6 | 72 | hr | 1401 | 2159 | 4168 | 0.5177 | 0.3152 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4442 | 4245 | 1.0468 | 1.0584 |
| SK-BR-3 | PIK-93 | 0.12 | uM | LJP5 | 72 | hr | 1401 | 4374 | 4245 | 1.0317 | 1.0410 |
| SK-BR-3 | PIK-93 | 0.37 | uM | LJP5 | 72 | hr | 1401 | 3898 | 4245 | 0.9224 | 0.9034 |
| SK-BR-3 | PIK-93 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 3491 | 4245 | 0.8242 | 0.7726 |
| SK-BR-3 | PIK-93 | 3.33 | uM | LJP5 | 72 | hr | 1401 | 3056 | 4245 | 0.7243 | 0.6350 |