LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 PD0325901
10
uM
LJP6
 72
hr
 1235 641 4405 0.1438 -0.3232
MDA-MB-231 Geldanamycin
0.04
uM
LJP5
 72
hr
 1235 2583 4660 0.5519 0.4620
MDA-MB-231 Geldanamycin
0.04
uM
LJP6
 72
hr
 1235 1876 4405 0.4230 0.2377
MDA-MB-231 Geldanamycin
0.12
uM
LJP5
 72
hr
 1235 1210 4660 0.2586 -0.0155
MDA-MB-231 Geldanamycin
0.12
uM
LJP6
 72
hr
 1235 1101 4405 0.2497 -0.0626
MDA-MB-231 Geldanamycin
0.37
uM
LJP5
 72
hr
 1235 944 4660 0.2028 -0.1319
MDA-MB-231 Geldanamycin
0.37
uM
LJP6
 72
hr
 1235 876 4405 0.1986 -0.1728
MDA-MB-231 Geldanamycin
1.11
uM
LJP5
 72
hr
 1235 842 4660 0.1811 -0.1815
MDA-MB-231 Geldanamycin
1.11
uM
LJP6
 72
hr
 1235 674 4405 0.1521 -0.2886
MDA-MB-231 Geldanamycin
3.33
uM
LJP5
 72
hr
 1235 743 4660 0.1595 -0.2339
MDA-MB-231 Geldanamycin
3.33
uM
LJP6
 72
hr
 1235 596 4405 0.1343 -0.3428
MDA-MB-231 Geldanamycin
10
uM
LJP5
 72
hr
 1235 541 4660 0.1163 -0.3517
MDA-MB-231 Geldanamycin
10
uM
LJP6
 72
hr
 1235 334 4405 0.0750 -0.5239
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4673 4660 1.0019 1.0012
MDA-MB-231 YM 201636
0.12
uM
LJP5
 72
hr
 1235 4204 4660 0.8999 0.8902
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 1235 3734 4660 0.7985 0.7746
MDA-MB-231 YM 201636
1.11
uM
LJP5
 72
hr
 1235 3223 4660 0.6888 0.6417
MDA-MB-231 YM 201636
3.33
uM
LJP5
 72
hr
 1235 2698 4660 0.5776 0.4991
MDA-MB-231 YM 201636
10
uM
LJP5
 72
hr
 1235 986 4660 0.2113 -0.1132
MDA-MB-231 TWS119
0.04
uM
LJP5
 72
hr
 1235 4320 4660 0.9235 0.9138
MDA-MB-231 TWS119
0.12
uM
LJP5
 72
hr
 1235 4211 4660 0.9012 0.8914
MDA-MB-231 TWS119
0.37
uM
LJP5
 72
hr
 1235 4018 4660 0.8611 0.8486
MDA-MB-231 TWS119
1.11
uM
LJP5
 72
hr
 1235 3605 4660 0.7727 0.7470
MDA-MB-231 TWS119
3.33
uM
LJP5
 72
hr
 1235 3040 4660 0.6522 0.5986
MDA-MB-231 TWS119
10
uM
LJP5
 72
hr
 1235 1299 4660 0.2794 0.0267