LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 72
hr
 1235 4226 4660 0.9057 0.8980
MDA-MB-231 Alpelisib
3.33
uM
LJP5
 72
hr
 1235 4249 4660 0.9106 0.9034
MDA-MB-231 Alpelisib
10
uM
LJP5
 72
hr
 1235 3575 4660 0.7665 0.7398
MDA-MB-231 GDC-0980
0.04
uM
LJP5
 72
hr
 1235 3197 4660 0.6871 0.6441
MDA-MB-231 GDC-0980
0.12
uM
LJP5
 72
hr
 1235 2564 4660 0.5497 0.4621
MDA-MB-231 GDC-0980
0.37
uM
LJP5
 72
hr
 1235 2022 4660 0.4338 0.2922
MDA-MB-231 GDC-0980
1.11
uM
LJP5
 72
hr
 1235 1700 4660 0.3639 0.1777
MDA-MB-231 GDC-0980
3.33
uM
LJP5
 72
hr
 1235 1550 4660 0.3319 0.1225
MDA-MB-231 GDC-0980
10
uM
LJP5
 72
hr
 1235 1280 4660 0.2742 0.0158
MDA-MB-231 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1235 1037 4660 0.2229 -0.0878
MDA-MB-231 Mitoxantrone
0.04
uM
LJP6
 72
hr
 1235 975 4405 0.2213 -0.1220
MDA-MB-231 Mitoxantrone
0.12
uM
LJP5
 72
hr
 1235 959 4660 0.2063 -0.1241
MDA-MB-231 Mitoxantrone
0.12
uM
LJP6
 72
hr
 1235 916 4405 0.2075 -0.1532
MDA-MB-231 Mitoxantrone
0.37
uM
LJP5
 72
hr
 1235 756 4660 0.1625 -0.2267
MDA-MB-231 Mitoxantrone
0.37
uM
LJP6
 72
hr
 1235 692 4405 0.1567 -0.2734
MDA-MB-231 Mitoxantrone
1.11
uM
LJP5
 72
hr
 1235 451 4660 0.0966 -0.4106
MDA-MB-231 Mitoxantrone
1.11
uM
LJP6
 72
hr
 1235 456 4405 0.1038 -0.4198
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 185 4660 0.0399 -0.6288
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4405 0.0467 -0.6246
MDA-MB-231 Mitoxantrone
10
uM
LJP5
 72
hr
 1235 86 4660 0.0186 -0.7515
MDA-MB-231 Mitoxantrone
10
uM
LJP6
 72
hr
 1235 108 4405 0.0247 -0.7348
MDA-MB-231 Radicicol
0.04
uM
LJP5
 72
hr
 1235 4718 4660 1.0129 1.0138
MDA-MB-231 Radicicol
0.04
uM
LJP6
 72
hr
 1235 4715 4405 1.0714 1.0773
MDA-MB-231 Radicicol
0.12
uM
LJP5
 72
hr
 1235 3425 4660 0.7340 0.6996
MDA-MB-231 Radicicol
0.12
uM
LJP6
 72
hr
 1235 3118 4405 0.7088 0.6577