LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MDA-MB-231 Radicicol
0.37
uM
LJP5
 72
hr
 1235 1705 4660 0.3654 0.1808
MDA-MB-231 Radicicol
0.37
uM
LJP6
 72
hr
 1235 1539 4405 0.3504 0.1274
MDA-MB-231 Radicicol
1.11
uM
LJP5
 72
hr
 1235 1004 4660 0.2151 -0.1047
MDA-MB-231 Radicicol
1.11
uM
LJP6
 72
hr
 1235 1180 4405 0.2688 -0.0255
MDA-MB-231 Radicicol
3.33
uM
LJP5
 72
hr
 1235 916 4660 0.1965 -0.1459
MDA-MB-231 Radicicol
3.33
uM
LJP6
 72
hr
 1235 1072 4405 0.2440 -0.0746
MDA-MB-231 Radicicol
10
uM
LJP5
 72
hr
 1235 971 4660 0.2079 -0.1220
MDA-MB-231 Radicicol
10
uM
LJP6
 72
hr
 1235 833 4405 0.1887 -0.1957
MDA-MB-231 Withaferin A
0.04
uM
LJP5
 72
hr
 1235 4860 4660 1.0433 1.0452
MDA-MB-231 Withaferin A
0.04
uM
LJP6
 72
hr
 1235 4613 4405 1.0473 1.0511
MDA-MB-231 Withaferin A
0.12
uM
LJP5
 72
hr
 1235 4923 4660 1.0567 1.0588
MDA-MB-231 Withaferin A
0.12
uM
LJP6
 72
hr
 1235 4250 4405 0.9646 0.9609
MDA-MB-231 Withaferin A
0.37
uM
LJP5
 72
hr
 1235 2841 4660 0.6068 0.5360
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 72
hr
 1235 2493 4405 0.5654 0.4641
MDA-MB-231 Withaferin A
1.11
uM
LJP5
 72
hr
 1235 1003 4660 0.2145 -0.1065
MDA-MB-231 Withaferin A
1.11
uM
LJP6
 72
hr
 1235 978 4405 0.2229 -0.1209
MDA-MB-231 Withaferin A
3.33
uM
LJP5
 72
hr
 1235 858 4660 0.1843 -0.1743
MDA-MB-231 Withaferin A
3.33
uM
LJP6
 72
hr
 1235 898 4405 0.2049 -0.1630
MDA-MB-231 Withaferin A
10
uM
LJP5
 72
hr
 1235 604 4660 0.1297 -0.3127
MDA-MB-231 Withaferin A
10
uM
LJP6
 72
hr
 1235 593 4405 0.1350 -0.3330
BT-20 Seliciclib
0.04
uM
LJP5
 72
hr
 1097 3909 3846 1.0169 1.0188
BT-20 Seliciclib
0.12
uM
LJP5
 72
hr
 1097 3839 3846 0.9988 0.9980
BT-20 Seliciclib
0.37
uM
LJP5
 72
hr
 1097 3440 3846 0.8945 0.8805
BT-20 Seliciclib
1.11
uM
LJP5
 72
hr
 1097 3081 3846 0.8022 0.7706
BT-20 Seliciclib
3.33
uM
LJP5
 72
hr
 1097 2834 3846 0.7370 0.6889