LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Seliciclib
10
uM
LJP5
 72
hr
 1097 1639 3846 0.4263 0.2482
BT-20 AT-7519
0.04
uM
LJP6
 72
hr
 1097 3026 3673 0.8238 0.7896
BT-20 AT-7519
0.12
uM
LJP6
 72
hr
 1097 1875 3673 0.5105 0.3589
BT-20 AT-7519
0.37
uM
LJP6
 72
hr
 1097 832 3673 0.2262 -0.1485
BT-20 AT-7519
1.11
uM
LJP6
 72
hr
 1097 588 3673 0.1600 -0.3020
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1097 540 3673 0.1468 -0.3382
BT-20 AT-7519
10
uM
LJP6
 72
hr
 1097 529 3673 0.1442 -0.3420
BT-20 AZD7762
0.04
uM
LJP6
 72
hr
 1097 3676 3673 1.0006 1.0000
BT-20 AZD7762
0.12
uM
LJP6
 72
hr
 1097 2846 3673 0.7742 0.7255
BT-20 AZD7762
0.37
uM
LJP6
 72
hr
 1097 2115 3673 0.5756 0.4564
BT-20 AZD7762
1.11
uM
LJP6
 72
hr
 1097 1307 3673 0.3559 0.1055
BT-20 AZD7762
3.33
uM
LJP6
 72
hr
 1097 750 3673 0.2042 -0.1962
BT-20 AZD7762
10
uM
LJP6
 72
hr
 1097 456 3673 0.1241 -0.3966
BT-20 AZD8055
0.04
uM
LJP6
 72
hr
 1097 1423 3673 0.3873 0.1601
BT-20 AZD8055
0.12
uM
LJP6
 72
hr
 1097 1170 3673 0.3188 0.0367
BT-20 AZD8055
0.37
uM
LJP6
 72
hr
 1097 1116 3673 0.3039 0.0097
BT-20 AZD8055
1.11
uM
LJP6
 72
hr
 1097 1050 3673 0.2858 -0.0251
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1097 906 3673 0.2468 -0.1038
BT-20 AZD8055
10
uM
LJP6
 72
hr
 1097 119 3673 0.0326 -0.7198
BT-20 Sorafenib
0.04
uM
LJP6
 72
hr
 1097 3411 3673 0.9288 0.9170
BT-20 Sorafenib
0.12
uM
LJP6
 72
hr
 1097 3487 3673 0.9497 0.9413
BT-20 Sorafenib
0.37
uM
LJP6
 72
hr
 1097 3050 3673 0.8306 0.7963
BT-20 Sorafenib
1.11
uM
LJP6
 72
hr
 1097 3091 3673 0.8415 0.8115
BT-20 Sorafenib
3.33
uM
LJP6
 72
hr
 1097 3110 3673 0.8471 0.8185
BT-20 Sorafenib
10
uM
LJP6
 72
hr
 1097 1328 3673 0.3613 0.1140