LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1059615
0.04
uM
LJP5
 72
hr
 962 10852 10512 1.0323 1.0185
MCF 10A GSK1059615
0.04
uM
LJP6
 72
hr
 962 10758 10692 1.0062 1.0035
MCF 10A GSK1059615
0.12
uM
LJP5
 72
hr
 962 10068 10512 0.9577 0.9750
MCF 10A GSK1059615
0.12
uM
LJP6
 72
hr
 962 9601 10692 0.8980 0.9390
MCF 10A GSK1059615
0.37
uM
LJP5
 72
hr
 962 5546 10512 0.5281 0.6616
MCF 10A GSK1059615
0.37
uM
LJP6
 72
hr
 962 7429 10692 0.6949 0.8008
MCF 10A GSK1059615
1.11
uM
LJP5
 72
hr
 962 1428 10512 0.1361 0.1209
MCF 10A GSK1059615
1.11
uM
LJP6
 72
hr
 962 1760 10692 0.1647 0.1896
MCF 10A GSK1059615
3.33
uM
LJP5
 72
hr
 962 806 10512 0.0768 -0.0511
MCF 10A GSK1059615
3.33
uM
LJP6
 72
hr
 962 745 10692 0.0697 -0.0725
MCF 10A GSK1059615
10
uM
LJP5
 72
hr
 962 480 10512 0.0457 -0.1828
MCF 10A GSK1059615
10
uM
LJP6
 72
hr
 962 491 10692 0.0460 -0.1764
MCF 10A Brivanib
0.04
uM
LJP5
 72
hr
 962 10548 10512 1.0036 1.0021
MCF 10A Brivanib
0.12
uM
LJP5
 72
hr
 962 10506 10512 0.9998 0.9998
MCF 10A Brivanib
0.37
uM
LJP5
 72
hr
 962 10111 10512 0.9622 0.9778
MCF 10A Brivanib
1.11
uM
LJP5
 72
hr
 962 9258 10512 0.8810 0.9279
MCF 10A Brivanib
3.33
uM
LJP5
 72
hr
 962 7242 10512 0.6892 0.7953
MCF 10A Brivanib
10
uM
LJP5
 72
hr
 962 2440 10512 0.2323 0.3095
MCF 10A CHIR-99021
0.04
uM
LJP6
 72
hr
 962 11451 10692 1.0711 1.0399
MCF 10A CHIR-99021
0.12
uM
LJP6
 72
hr
 962 11249 10692 1.0522 1.0294
MCF 10A CHIR-99021
0.37
uM
LJP6
 72
hr
 962 11501 10692 1.0758 1.0424
MCF 10A CHIR-99021
1.11
uM
LJP6
 72
hr
 962 11066 10692 1.0351 1.0198
MCF 10A CHIR-99021
3.33
uM
LJP6
 72
hr
 962 10194 10692 0.9534 0.9727
MCF 10A CHIR-99021
10
uM
LJP6
 72
hr
 962 8827 10692 0.8254 0.8918
MCF 10A Linifanib
0.04
uM
LJP6
 72
hr
 962 11413 10692 1.0675 1.0380