LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XMD11-85h
0.37
uM
LJP6
 72
hr
 962 10650 10692 0.9961 0.9977
MCF 10A XMD11-85h
1.11
uM
LJP6
 72
hr
 962 10543 10692 0.9861 0.9919
MCF 10A XMD11-85h
3.33
uM
LJP6
 72
hr
 962 10124 10692 0.9470 0.9689
MCF 10A XMD11-85h
10
uM
LJP6
 72
hr
 962 6201 10692 0.5800 0.7096
MCF 10A XMD16-144
0.04
uM
LJP5
 72
hr
 962 2697 10512 0.2566 0.3474
MCF 10A XMD16-144
0.12
uM
LJP5
 72
hr
 962 1452 10512 0.1382 0.1267
MCF 10A XMD16-144
0.37
uM
LJP5
 72
hr
 962 1603 10512 0.1526 0.1594
MCF 10A XMD16-144
1.11
uM
LJP5
 72
hr
 962 1438 10512 0.1369 0.1236
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 962 1265 10512 0.1204 0.0824
MCF 10A XMD16-144
10
uM
LJP5
 72
hr
 962 979 10512 0.0932 0.0040
MCF 10A Erlotinib
0.04
uM
LJP5
 72
hr
 962 9767 10512 0.9292 0.9579
MCF 10A Erlotinib
0.12
uM
LJP5
 72
hr
 962 5630 10512 0.5359 0.6690
MCF 10A Erlotinib
0.37
uM
LJP5
 72
hr
 962 2213 10512 0.2107 0.2731
MCF 10A Erlotinib
1.11
uM
LJP5
 72
hr
 962 1460 10512 0.1390 0.1284
MCF 10A Erlotinib
3.33
uM
LJP5
 72
hr
 962 1534 10512 0.1460 0.1446
MCF 10A Erlotinib
10
uM
LJP5
 72
hr
 962 1501 10512 0.1429 0.1375
MCF 10A Gefitinib
0.04
uM
LJP6
 72
hr
 962 9196 10692 0.8601 0.9151
MCF 10A Gefitinib
0.12
uM
LJP6
 72
hr
 962 5221 10692 0.4883 0.6271
MCF 10A Gefitinib
0.37
uM
LJP6
 72
hr
 962 2267 10692 0.2120 0.2795
MCF 10A Gefitinib
1.11
uM
LJP6
 72
hr
 962 1470 10692 0.1375 0.1297
MCF 10A Gefitinib
3.33
uM
LJP6
 72
hr
 962 1402 10692 0.1311 0.1143
MCF 10A Gefitinib
10
uM
LJP6
 72
hr
 962 1262 10692 0.1181 0.0803
MCF 10A Nilotinib
0.04
uM
LJP5
 72
hr
 962 9781 10512 0.9306 0.9587
MCF 10A Nilotinib
0.12
uM
LJP5
 72
hr
 962 9650 10512 0.9180 0.9508
MCF 10A Nilotinib
0.37
uM
LJP5
 72
hr
 962 9569 10512 0.9101 0.9460