LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Torin2
0.12
uM
LJP5
 72
hr
 962 1535 10512 0.1461 0.1448
MCF 10A Torin2
0.37
uM
LJP5
 72
hr
 962 1347 10512 0.1284 0.1016
MCF 10A Torin2
1.11
uM
LJP5
 72
hr
 962 1106 10512 0.1052 0.0403
MCF 10A Torin2
3.33
uM
LJP5
 72
hr
 962 1380 10512 0.1319 0.0987
MCF 10A Torin2
10
uM
LJP5
 72
hr
 962 1277 10512 0.1220 0.0767
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 962 10423 10692 0.9749 0.9854
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 962 9948 10692 0.9305 0.9589
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 962 9478 10692 0.8865 0.9319
MCF 10A WZ-4-145
1.11
uM
LJP6
 72
hr
 962 7948 10692 0.7434 0.8363
MCF 10A WZ-4-145
3.33
uM
LJP6
 72
hr
 962 5531 10692 0.5174 0.6544
MCF 10A WZ-4-145
10
uM
LJP6
 72
hr
 962 1004 10692 0.0939 0.0118
MCF 10A WZ3105
0.04
uM
LJP5
 72
hr
 962 4977 10512 0.4739 0.6098
MCF 10A WZ3105
0.12
uM
LJP5
 72
hr
 962 1505 10512 0.1433 0.1385
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 962 522 10512 0.0498 -0.1629
MCF 10A WZ3105
1.11
uM
LJP5
 72
hr
 962 254 10512 0.0242 -0.3207
MCF 10A WZ3105
3.33
uM
LJP5
 72
hr
 962 211 10512 0.0201 -0.3563
MCF 10A WZ3105
10
uM
LJP5
 72
hr
 962 185 10512 0.0176 -0.3840
MCF 10A XMD11-50
0.04
uM
LJP6
 72
hr
 962 10001 10692 0.9354 0.9619
MCF 10A XMD11-50
0.12
uM
LJP6
 72
hr
 962 9197 10692 0.8602 0.9152
MCF 10A XMD11-50
0.37
uM
LJP6
 72
hr
 962 7667 10692 0.7170 0.8173
MCF 10A XMD11-50
1.11
uM
LJP6
 72
hr
 962 5190 10692 0.4853 0.6235
MCF 10A XMD11-50
3.33
uM
LJP6
 72
hr
 962 2653 10692 0.2481 0.3390
MCF 10A XMD11-50
10
uM
LJP6
 72
hr
 962 1194 10692 0.1117 0.0641
MCF 10A XMD11-85h
0.04
uM
LJP6
 72
hr
 962 10945 10692 1.0238 1.0134
MCF 10A XMD11-85h
0.12
uM
LJP6
 72
hr
 962 10944 10692 1.0236 1.0135