LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Neratinib
1.11
uM
LJP5
 72
hr
 962 1596 10512 0.1519 0.1578
MCF 10A Neratinib
3.33
uM
LJP5
 72
hr
 962 1517 10512 0.1444 0.1410
MCF 10A Neratinib
10
uM
LJP5
 72
hr
 962 1606 10512 0.1528 0.1592
MCF 10A JW-7-24-1
0.04
uM
LJP6
 72
hr
 962 10930 10692 1.0224 1.0127
MCF 10A JW-7-24-1
0.12
uM
LJP6
 72
hr
 962 10510 10692 0.9830 0.9902
MCF 10A JW-7-24-1
0.37
uM
LJP6
 72
hr
 962 9787 10692 0.9155 0.9497
MCF 10A JW-7-24-1
1.11
uM
LJP6
 72
hr
 962 8711 10692 0.8149 0.8853
MCF 10A JW-7-24-1
3.33
uM
LJP6
 72
hr
 962 6900 10692 0.6454 0.7630
MCF 10A JW-7-24-1
10
uM
LJP6
 72
hr
 962 1460 10692 0.1366 0.1269
MCF 10A Dasatinib
0.04
uM
LJP5
 72
hr
 962 8953 10512 0.8512 0.9084
MCF 10A Dasatinib
0.04
uM
LJP6
 72
hr
 962 2885 10692 0.2698 0.3713
MCF 10A Dasatinib
0.12
uM
LJP5
 72
hr
 962 6164 10512 0.5864 0.7129
MCF 10A Dasatinib
0.12
uM
LJP6
 72
hr
 962 2316 10692 0.2167 0.2878
MCF 10A Dasatinib
0.37
uM
LJP5
 72
hr
 962 3086 10512 0.2937 0.4020
MCF 10A Dasatinib
0.37
uM
LJP6
 72
hr
 962 2012 10692 0.1882 0.2366
MCF 10A Dasatinib
1.11
uM
LJP5
 72
hr
 962 1923 10512 0.1831 0.2223
MCF 10A Dasatinib
1.11
uM
LJP6
 72
hr
 962 1272 10692 0.1190 0.0829
MCF 10A Dasatinib
3.33
uM
LJP5
 72
hr
 962 1276 10512 0.1216 0.0835
MCF 10A Dasatinib
3.33
uM
LJP6
 72
hr
 962 970 10692 0.0908 0.0014
MCF 10A Dasatinib
10
uM
LJP5
 72
hr
 962 782 10512 0.0744 -0.0587
MCF 10A Dasatinib
10
uM
LJP6
 72
hr
 962 514 10692 0.0481 -0.1662
MCF 10A Tozasertib
0.04
uM
LJP5
 72
hr
 962 2070 10512 0.1971 0.2487
MCF 10A Tozasertib
0.12
uM
LJP5
 72
hr
 962 1486 10512 0.1414 0.1344
MCF 10A Tozasertib
0.37
uM
LJP5
 72
hr
 962 1384 10512 0.1316 0.1108
MCF 10A Tozasertib
1.11
uM
LJP5
 72
hr
 962 1389 10512 0.1322 0.1117