LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GW843682X
0.37
uM
LJP6
 72
hr
 962 2477 10692 0.2318 0.3123
MCF 10A GW843682X
1.11
uM
LJP6
 72
hr
 962 1036 10692 0.0969 0.0204
MCF 10A GW843682X
3.33
uM
LJP6
 72
hr
 962 647 10692 0.0606 -0.1084
MCF 10A GW843682X
10
uM
LJP6
 72
hr
 962 661 10692 0.0619 -0.1046
MCF 10A HG-5-113-01
0.04
uM
LJP5
 72
hr
 962 10133 10512 0.9641 0.9788
MCF 10A HG-5-113-01
0.12
uM
LJP5
 72
hr
 962 9832 10512 0.9353 0.9615
MCF 10A HG-5-113-01
0.37
uM
LJP5
 72
hr
 962 8630 10512 0.8209 0.8887
MCF 10A HG-5-113-01
1.11
uM
LJP5
 72
hr
 962 6186 10512 0.5885 0.7147
MCF 10A HG-5-113-01
3.33
uM
LJP5
 72
hr
 962 1672 10512 0.1590 0.1733
MCF 10A HG-5-113-01
10
uM
LJP5
 72
hr
 962 836 10512 0.0796 -0.0401
MCF 10A HG-5-88-01
0.04
uM
LJP6
 72
hr
 962 10682 10692 0.9991 0.9995
MCF 10A HG-5-88-01
0.12
uM
LJP6
 72
hr
 962 9724 10692 0.9095 0.9461
MCF 10A HG-5-88-01
0.37
uM
LJP6
 72
hr
 962 8600 10692 0.8044 0.8786
MCF 10A HG-5-88-01
1.11
uM
LJP6
 72
hr
 962 8375 10692 0.7834 0.8642
MCF 10A HG-5-88-01
3.33
uM
LJP6
 72
hr
 962 7811 10692 0.7305 0.8271
MCF 10A HG-5-88-01
10
uM
LJP6
 72
hr
 962 3772 10692 0.3529 0.4816
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 962 10078 10692 0.9425 0.9661
MCF 10A HG-6-64-01
0.12
uM
LJP6
 72
hr
 962 10055 10692 0.9404 0.9649
MCF 10A HG-6-64-01
0.37
uM
LJP6
 72
hr
 962 10342 10692 0.9673 0.9809
MCF 10A HG-6-64-01
1.11
uM
LJP6
 72
hr
 962 9196 10692 0.8601 0.9151
MCF 10A HG-6-64-01
3.33
uM
LJP6
 72
hr
 962 6155 10692 0.5756 0.7055
MCF 10A HG-6-64-01
10
uM
LJP6
 72
hr
 962 824 10692 0.0771 -0.0437
MCF 10A Neratinib
0.04
uM
LJP5
 72
hr
 962 4873 10512 0.4634 0.5991
MCF 10A Neratinib
0.12
uM
LJP5
 72
hr
 962 3269 10512 0.3111 0.4255
MCF 10A Neratinib
0.37
uM
LJP5
 72
hr
 962 1603 10512 0.1524 0.1587