LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SNS-032
3.33
uM
LJP6
 72
hr
 658 532 3761 0.1417 -0.0809
Hs 578T SNS-032
10
uM
LJP6
 72
hr
 658 519 3761 0.1381 -0.0899
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3761 0.9457 0.9560
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 658 3670 3761 0.9759 0.9806
Hs 578T Afatinib
0.37
uM
LJP6
 72
hr
 658 3611 3761 0.9601 0.9678
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 658 3341 3761 0.8883 0.9080
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 658 3389 3761 0.9013 0.9190
Hs 578T Afatinib
10
uM
LJP6
 72
hr
 658 457 3761 0.1215 -0.1351
Hs 578T GSK1904529A
0.04
uM
LJP6
 72
hr
 658 3453 3761 0.9182 0.9332
Hs 578T GSK1904529A
0.12
uM
LJP6
 72
hr
 658 3573 3761 0.9503 0.9597
Hs 578T GSK1904529A
0.37
uM
LJP6
 72
hr
 658 3526 3761 0.9373 0.9489
Hs 578T GSK1904529A
1.11
uM
LJP6
 72
hr
 658 3566 3761 0.9483 0.9582
Hs 578T GSK1904529A
3.33
uM
LJP6
 72
hr
 658 3667 3761 0.9751 0.9800
Hs 578T GSK1904529A
10
uM
LJP6
 72
hr
 658 3670 3761 0.9757 0.9804
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 658 3634 3933 0.9241 0.9397
Hs 578T Linsitinib
0.12
uM
LJP5
 72
hr
 658 3756 3933 0.9550 0.9645
Hs 578T Linsitinib
0.37
uM
LJP5
 72
hr
 658 3557 3933 0.9042 0.9234
Hs 578T Linsitinib
1.11
uM
LJP5
 72
hr
 658 3586 3933 0.9116 0.9294
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 658 3644 3933 0.9264 0.9415
Hs 578T Linsitinib
10
uM
LJP5
 72
hr
 658 3511 3933 0.8927 0.9139
Hs 578T Ruxolitinib
0.04
uM
LJP5
 72
hr
 658 3861 3933 0.9815 0.9854
Hs 578T Ruxolitinib
0.12
uM
LJP5
 72
hr
 658 3642 3933 0.9260 0.9412
Hs 578T Ruxolitinib
0.37
uM
LJP5
 72
hr
 658 3683 3933 0.9363 0.9495
Hs 578T Ruxolitinib
1.11
uM
LJP5
 72
hr
 658 3717 3933 0.9451 0.9566
Hs 578T Ruxolitinib
3.33
uM
LJP5
 72
hr
 658 3559 3933 0.9048 0.9235