LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T PHA-665752
1.11
uM
LJP5
 72
hr
 658 3570 3933 0.9072 0.9232
Hs 578T PHA-665752
3.33
uM
LJP5
 72
hr
 658 3707 3933 0.9424 0.9545
Hs 578T PHA-665752
10
uM
LJP5
 72
hr
 658 53 3933 0.0136 -0.6240
Hs 578T PI103
0.04
uM
LJP6
 72
hr
 658 2365 3761 0.6291 0.6633
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 658 1774 3761 0.4718 0.4834
Hs 578T PI103
0.37
uM
LJP6
 72
hr
 658 1504 3761 0.3998 0.3883
Hs 578T PI103
1.11
uM
LJP6
 72
hr
 658 1309 3761 0.3482 0.3146
Hs 578T PI103
3.33
uM
LJP6
 72
hr
 658 1230 3761 0.3271 0.2823
Hs 578T PI103
10
uM
LJP6
 72
hr
 658 909 3761 0.2419 0.1370
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 658 3188 3933 0.8105 0.8433
Hs 578T Dovitinib
0.12
uM
LJP5
 72
hr
 658 2222 3933 0.5649 0.6022
Hs 578T Dovitinib
0.37
uM
LJP5
 72
hr
 658 1103 3933 0.2805 0.2217
Hs 578T Dovitinib
1.11
uM
LJP5
 72
hr
 658 1029 3933 0.2616 0.1890
Hs 578T Dovitinib
3.33
uM
LJP5
 72
hr
 658 1204 3933 0.3061 0.2637
Hs 578T Dovitinib
10
uM
LJP5
 72
hr
 658 868 3933 0.2208 0.1133
Hs 578T GSK 690693
0.04
uM
LJP5
 72
hr
 658 3424 3933 0.8704 0.8950
Hs 578T GSK 690693
0.12
uM
LJP5
 72
hr
 658 3357 3933 0.8534 0.8808
Hs 578T GSK 690693
0.37
uM
LJP5
 72
hr
 658 3094 3933 0.7867 0.8223
Hs 578T GSK 690693
1.11
uM
LJP5
 72
hr
 658 3159 3933 0.8032 0.8369
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 658 3296 3933 0.8381 0.8673
Hs 578T GSK 690693
10
uM
LJP5
 72
hr
 658 3279 3933 0.8337 0.8637
Hs 578T SNS-032
0.04
uM
LJP6
 72
hr
 658 2942 3761 0.7826 0.8142
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 658 542 3761 0.1444 -0.0741
Hs 578T SNS-032
0.37
uM
LJP6
 72
hr
 658 518 3761 0.1377 -0.0917
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 658 548 3761 0.1457 -0.0704