LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Celastrol
0.37
uM
LJP6
 72
hr
 658 3127 3761 0.8315 0.8585
Hs 578T Celastrol
1.11
uM
LJP6
 72
hr
 658 520 3761 0.1384 -0.0890
Hs 578T Celastrol
3.33
uM
LJP6
 72
hr
 658 627 3761 0.1668 -0.0201
Hs 578T Celastrol
10
uM
LJP6
 72
hr
 658 235 3761 0.0625 -0.3377
Hs 578T SU11274
0.04
uM
LJP5
 72
hr
 658 3965 3933 1.0080 1.0059
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 658 3851 3933 0.9791 0.9837
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 658 3698 3933 0.9401 0.9525
Hs 578T SU11274
1.11
uM
LJP5
 72
hr
 658 3493 3933 0.8880 0.9098
Hs 578T SU11274
3.33
uM
LJP5
 72
hr
 658 3226 3933 0.8202 0.8519
Hs 578T SU11274
10
uM
LJP5
 72
hr
 658 966 3933 0.2458 0.1607
Hs 578T Canertinib
0.04
uM
LJP6
 72
hr
 658 3904 3761 1.0383 1.0302
Hs 578T Canertinib
0.12
uM
LJP6
 72
hr
 658 3894 3761 1.0355 1.0279
Hs 578T Canertinib
0.37
uM
LJP6
 72
hr
 658 3709 3761 0.9865 0.9891
Hs 578T Canertinib
1.11
uM
LJP6
 72
hr
 658 3549 3761 0.9438 0.9545
Hs 578T Canertinib
3.33
uM
LJP6
 72
hr
 658 3099 3761 0.8238 0.8514
Hs 578T Canertinib
10
uM
LJP6
 72
hr
 658 351 3761 0.0934 -0.2217
Hs 578T NVP-AEW541
0.04
uM
LJP5
 72
hr
 658 3972 3933 1.0100 1.0076
Hs 578T NVP-AEW541
0.12
uM
LJP5
 72
hr
 658 3994 3933 1.0155 1.0119
Hs 578T NVP-AEW541
0.37
uM
LJP5
 72
hr
 658 4004 3933 1.0180 1.0134
Hs 578T NVP-AEW541
1.11
uM
LJP5
 72
hr
 658 3748 3933 0.9530 0.9630
Hs 578T NVP-AEW541
3.33
uM
LJP5
 72
hr
 658 3948 3933 1.0036 1.0027
Hs 578T NVP-AEW541
10
uM
LJP5
 72
hr
 658 945 3933 0.2402 0.1493
Hs 578T PHA-665752
0.04
uM
LJP5
 72
hr
 658 4007 3933 1.0187 1.0144
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 658 3930 3933 0.9993 0.9995
Hs 578T PHA-665752
0.37
uM
LJP5
 72
hr
 658 3966 3933 1.0084 1.0064