LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Seliciclib
0.04
uM
LJP5
 72
hr
 962 10269 10512 0.9769 0.9865
MCF 10A Seliciclib
0.12
uM
LJP5
 72
hr
 962 10036 10512 0.9547 0.9731
MCF 10A Seliciclib
0.37
uM
LJP5
 72
hr
 962 9671 10512 0.9201 0.9523
MCF 10A Seliciclib
1.11
uM
LJP5
 72
hr
 962 9451 10512 0.8993 0.9393
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 962 8937 10512 0.8501 0.9079
MCF 10A Seliciclib
10
uM
LJP5
 72
hr
 962 4858 10512 0.4626 0.5989
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 962 9592 10692 0.8971 0.9382
MCF 10A AT-7519
0.12
uM
LJP6
 72
hr
 962 7625 10692 0.7132 0.8145
MCF 10A AT-7519
0.37
uM
LJP6
 72
hr
 962 595 10692 0.0557 -0.1298
MCF 10A AT-7519
1.11
uM
LJP6
 72
hr
 962 319 10692 0.0299 -0.2726
MCF 10A AT-7519
3.33
uM
LJP6
 72
hr
 962 194 10692 0.0181 -0.3695
MCF 10A AT-7519
10
uM
LJP6
 72
hr
 962 195 10692 0.0183 -0.3686
MCF 10A AZD7762
0.04
uM
LJP6
 72
hr
 962 10030 10692 0.9381 0.9634
MCF 10A AZD7762
0.12
uM
LJP6
 72
hr
 962 8295 10692 0.7759 0.8591
MCF 10A AZD7762
0.37
uM
LJP6
 72
hr
 962 6489 10692 0.6069 0.7322
MCF 10A AZD7762
1.11
uM
LJP6
 72
hr
 962 3756 10692 0.3513 0.4793
MCF 10A AZD7762
3.33
uM
LJP6
 72
hr
 962 1659 10692 0.1552 0.1693
MCF 10A AZD7762
10
uM
LJP6
 72
hr
 962 414 10692 0.0388 -0.2181
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 962 3374 10692 0.3157 0.4335
MCF 10A AZD8055
0.12
uM
LJP6
 72
hr
 962 2256 10692 0.2111 0.2779
MCF 10A AZD8055
0.37
uM
LJP6
 72
hr
 962 1649 10692 0.1543 0.1674
MCF 10A AZD8055
1.11
uM
LJP6
 72
hr
 962 1540 10692 0.1441 0.1450
MCF 10A AZD8055
3.33
uM
LJP6
 72
hr
 962 1501 10692 0.1404 0.1361
MCF 10A AZD8055
10
uM
LJP6
 72
hr
 962 57 10692 0.0053 -0.5572
MCF 10A Sorafenib
0.04
uM
LJP6
 72
hr
 962 10167 10692 0.9510 0.9711