LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD-6482
3.33
uM
LJP5
 72
hr
 962 9766 10512 0.9293 0.9578
MCF 10A AZD-6482
10
uM
LJP5
 72
hr
 962 4647 10512 0.4426 0.5782
MCF 10A NU7441
0.04
uM
LJP5
 72
hr
 962 10789 10512 1.0262 1.0149
MCF 10A NU7441
0.12
uM
LJP5
 72
hr
 962 10592 10512 1.0075 1.0042
MCF 10A NU7441
0.37
uM
LJP5
 72
hr
 962 10097 10512 0.9605 0.9768
MCF 10A NU7441
1.11
uM
LJP5
 72
hr
 962 9609 10512 0.9139 0.9483
MCF 10A NU7441
3.33
uM
LJP5
 72
hr
 962 8446 10512 0.8033 0.8769
MCF 10A NU7441
10
uM
LJP5
 72
hr
 962 1833 10512 0.1741 0.2021
MCF 10A OSI-027
0.04
uM
LJP6
 72
hr
 962 7454 10692 0.6974 0.8022
MCF 10A OSI-027
0.12
uM
LJP6
 72
hr
 962 4669 10692 0.4368 0.5754
MCF 10A OSI-027
0.37
uM
LJP6
 72
hr
 962 2731 10692 0.2555 0.3497
MCF 10A OSI-027
1.11
uM
LJP6
 72
hr
 962 2181 10692 0.2040 0.2650
MCF 10A OSI-027
3.33
uM
LJP6
 72
hr
 962 1575 10692 0.1473 0.1520
MCF 10A OSI-027
10
uM
LJP6
 72
hr
 962 1514 10692 0.1416 0.1389
MCF 10A WYE-125132
0.04
uM
LJP6
 72
hr
 962 3086 10692 0.2887 0.3982
MCF 10A WYE-125132
0.12
uM
LJP6
 72
hr
 962 1947 10692 0.1821 0.2250
MCF 10A WYE-125132
0.37
uM
LJP6
 72
hr
 962 1620 10692 0.1515 0.1614
MCF 10A WYE-125132
1.11
uM
LJP6
 72
hr
 962 1607 10692 0.1504 0.1592
MCF 10A WYE-125132
3.33
uM
LJP6
 72
hr
 962 1417 10692 0.1325 0.1179
MCF 10A WYE-125132
10
uM
LJP6
 72
hr
 962 1427 10692 0.1335 0.1201
MCF 10A Barasertib
0.04
uM
LJP5
 72
hr
 962 1437 10512 0.1367 0.1230
MCF 10A Barasertib
0.12
uM
LJP5
 72
hr
 962 1429 10512 0.1361 0.1215
MCF 10A Barasertib
0.37
uM
LJP5
 72
hr
 962 1401 10512 0.1333 0.1144
MCF 10A Barasertib
1.11
uM
LJP5
 72
hr
 962 1466 10512 0.1395 0.1298
MCF 10A Barasertib
3.33
uM
LJP5
 72
hr
 962 1494 10512 0.1421 0.1359