LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Barasertib
10
uM
LJP5
 72
hr
 962 1465 10512 0.1394 0.1281
MCF 10A Vemurafenib
0.04
uM
LJP5
 72
hr
 962 10399 10512 0.9892 0.9936
MCF 10A Vemurafenib
0.12
uM
LJP5
 72
hr
 962 10238 10512 0.9740 0.9848
MCF 10A Vemurafenib
0.37
uM
LJP5
 72
hr
 962 10309 10512 0.9806 0.9886
MCF 10A Vemurafenib
1.11
uM
LJP5
 72
hr
 962 10108 10512 0.9615 0.9773
MCF 10A Vemurafenib
3.33
uM
LJP5
 72
hr
 962 8735 10512 0.8312 0.8954
MCF 10A Vemurafenib
10
uM
LJP5
 72
hr
 962 4165 10512 0.3960 0.5283
MCF 10A Enzastaurin
0.04
uM
LJP5
 72
hr
 962 10758 10512 1.0234 1.0134
MCF 10A Enzastaurin
0.12
uM
LJP5
 72
hr
 962 10762 10512 1.0237 1.0136
MCF 10A Enzastaurin
0.37
uM
LJP5
 72
hr
 962 10851 10512 1.0323 1.0184
MCF 10A Enzastaurin
1.11
uM
LJP5
 72
hr
 962 11253 10512 1.0703 1.0397
MCF 10A Enzastaurin
3.33
uM
LJP5
 72
hr
 962 11572 10512 1.1008 1.0564
MCF 10A Enzastaurin
10
uM
LJP5
 72
hr
 962 11123 10512 1.0580 1.0328
MCF 10A Palbociclib
0.04
uM
LJP6
 72
hr
 962 7377 10692 0.6900 0.7974
MCF 10A Palbociclib
0.12
uM
LJP6
 72
hr
 962 5870 10692 0.5491 0.6830
MCF 10A Palbociclib
0.37
uM
LJP6
 72
hr
 962 5066 10692 0.4739 0.6131
MCF 10A Palbociclib
1.11
uM
LJP6
 72
hr
 962 4339 10692 0.4058 0.5427
MCF 10A Palbociclib
3.33
uM
LJP6
 72
hr
 962 4065 10692 0.3803 0.5137
MCF 10A Palbociclib
10
uM
LJP6
 72
hr
 962 2737 10692 0.2560 0.3510
MCF 10A PF562271
0.04
uM
LJP6
 72
hr
 962 8699 10692 0.8137 0.8847
MCF 10A PF562271
0.12
uM
LJP6
 72
hr
 962 7356 10692 0.6881 0.7958
MCF 10A PF562271
0.37
uM
LJP6
 72
hr
 962 5456 10692 0.5103 0.6478
MCF 10A PF562271
1.11
uM
LJP6
 72
hr
 962 2906 10692 0.2719 0.3744
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 962 1254 10692 0.1173 0.0785
MCF 10A PF562271
10
uM
LJP6
 72
hr
 962 369 10692 0.0345 -0.2412