LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A ZSTK474
1.11
uM
LJP6
 72
hr
 962 3769 10692 0.3525 0.4811
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 962 2212 10692 0.2069 0.2708
MCF 10A ZSTK474
10
uM
LJP6
 72
hr
 962 1349 10692 0.1263 0.1021
MCF 10A BX-912
0.04
uM
LJP5
 72
hr
 962 9662 10512 0.9191 0.9516
MCF 10A BX-912
0.12
uM
LJP5
 72
hr
 962 8016 10512 0.7625 0.8487
MCF 10A BX-912
0.37
uM
LJP5
 72
hr
 962 2387 10512 0.2274 0.3011
MCF 10A BX-912
1.11
uM
LJP5
 72
hr
 962 1658 10512 0.1579 0.1709
MCF 10A BX-912
3.33
uM
LJP5
 72
hr
 962 1609 10512 0.1532 0.1608
MCF 10A BX-912
10
uM
LJP5
 72
hr
 962 1162 10512 0.1106 0.0562
MCF 10A Selumetinib
0.04
uM
LJP6
 72
hr
 962 4977 10692 0.4655 0.6048
MCF 10A Selumetinib
0.12
uM
LJP6
 72
hr
 962 3938 10692 0.3683 0.4997
MCF 10A Selumetinib
0.37
uM
LJP6
 72
hr
 962 3234 10692 0.3024 0.4163
MCF 10A Selumetinib
1.11
uM
LJP6
 72
hr
 962 2544 10692 0.2380 0.3226
MCF 10A Selumetinib
3.33
uM
LJP6
 72
hr
 962 2226 10692 0.2082 0.2728
MCF 10A Selumetinib
10
uM
LJP6
 72
hr
 962 1692 10692 0.1583 0.1759
MCF 10A MK2206
0.04
uM
LJP6
 72
hr
 962 9755 10692 0.9124 0.9479
MCF 10A MK2206
0.12
uM
LJP6
 72
hr
 962 9561 10692 0.8942 0.9366
MCF 10A MK2206
0.37
uM
LJP6
 72
hr
 962 9288 10692 0.8686 0.9201
MCF 10A MK2206
1.11
uM
LJP6
 72
hr
 962 8441 10692 0.7895 0.8684
MCF 10A MK2206
3.33
uM
LJP6
 72
hr
 962 7707 10692 0.7209 0.8202
MCF 10A MK2206
10
uM
LJP6
 72
hr
 962 2924 10692 0.2735 0.3770
MCF 10A AZD-6482
0.04
uM
LJP5
 72
hr
 962 10549 10512 1.0034 1.0019
MCF 10A AZD-6482
0.12
uM
LJP5
 72
hr
 962 10337 10512 0.9834 0.9902
MCF 10A AZD-6482
0.37
uM
LJP5
 72
hr
 962 10138 10512 0.9645 0.9791
MCF 10A AZD-6482
1.11
uM
LJP5
 72
hr
 962 10023 10512 0.9537 0.9727