LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A PD184352
0.37
uM
LJP5
 72
hr
 962 3931 10512 0.3738 0.5033
MCF 10A PD184352
1.11
uM
LJP5
 72
hr
 962 3432 10512 0.3264 0.4450
MCF 10A PD184352
3.33
uM
LJP5
 72
hr
 962 2663 10512 0.2533 0.3430
MCF 10A PD184352
10
uM
LJP5
 72
hr
 962 1578 10512 0.1501 0.1533
MCF 10A PLX-4720
0.04
uM
LJP5
 72
hr
 962 10086 10512 0.9595 0.9760
MCF 10A PLX-4720
0.12
uM
LJP5
 72
hr
 962 9619 10512 0.9150 0.9489
MCF 10A PLX-4720
0.37
uM
LJP5
 72
hr
 962 9239 10512 0.8789 0.9264
MCF 10A PLX-4720
1.11
uM
LJP5
 72
hr
 962 9201 10512 0.8754 0.9242
MCF 10A PLX-4720
3.33
uM
LJP5
 72
hr
 962 9312 10512 0.8860 0.9309
MCF 10A PLX-4720
10
uM
LJP5
 72
hr
 962 8942 10512 0.8511 0.9085
MCF 10A Lapatinib
0.04
uM
LJP6
 72
hr
 962 10747 10692 1.0052 1.0030
MCF 10A Lapatinib
0.12
uM
LJP6
 72
hr
 962 10580 10692 0.9895 0.9939
MCF 10A Lapatinib
0.37
uM
LJP6
 72
hr
 962 10615 10692 0.9929 0.9959
MCF 10A Lapatinib
1.11
uM
LJP6
 72
hr
 962 10191 10692 0.9533 0.9726
MCF 10A Lapatinib
3.33
uM
LJP6
 72
hr
 962 8583 10692 0.8028 0.8774
MCF 10A Lapatinib
10
uM
LJP6
 72
hr
 962 2659 10692 0.2487 0.3382
MCF 10A Sirolimus
0.04
uM
LJP6
 72
hr
 962 9348 10692 0.8743 0.9241
MCF 10A Sirolimus
0.12
uM
LJP6
 72
hr
 962 9527 10692 0.8911 0.9347
MCF 10A Sirolimus
0.37
uM
LJP6
 72
hr
 962 9293 10692 0.8691 0.9207
MCF 10A Sirolimus
1.11
uM
LJP6
 72
hr
 962 9424 10692 0.8814 0.9286
MCF 10A Sirolimus
3.33
uM
LJP6
 72
hr
 962 9200 10692 0.8605 0.9152
MCF 10A Sirolimus
10
uM
LJP6
 72
hr
 962 9031 10692 0.8446 0.9049
MCF 10A ZSTK474
0.04
uM
LJP6
 72
hr
 962 10688 10692 0.9996 0.9996
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 962 9117 10692 0.8526 0.9099
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 962 7328 10692 0.6853 0.7934