LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A BI-2536
0.12
uM
LJP6
 72
hr
 962 898 10692 0.0840 -0.0197
MCF 10A BI-2536
0.37
uM
LJP6
 72
hr
 962 1000 10692 0.0935 0.0110
MCF 10A BI-2536
1.11
uM
LJP6
 72
hr
 962 963 10692 0.0901 0.0002
MCF 10A BI-2536
3.33
uM
LJP6
 72
hr
 962 905 10692 0.0847 -0.0176
MCF 10A BI-2536
10
uM
LJP6
 72
hr
 962 909 10692 0.0851 -0.0170
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 962 10928 10692 1.0221 1.0126
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 962 7796 10692 0.7293 0.8261
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 962 1706 10692 0.1597 0.1792
MCF 10A A443654
1.11
uM
LJP6
 72
hr
 962 674 10692 0.0631 -0.0979
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 962 316 10692 0.0296 -0.2756
MCF 10A A443654
10
uM
LJP6
 72
hr
 962 173 10692 0.0162 -0.3911
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 962 8969 10512 0.8534 0.9101
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 962 8893 10512 0.8460 0.9052
MCF 10A SB590885
0.37
uM
LJP5
 72
hr
 962 9190 10512 0.8741 0.9234
MCF 10A SB590885
1.11
uM
LJP5
 72
hr
 962 9627 10512 0.9157 0.9495
MCF 10A SB590885
3.33
uM
LJP5
 72
hr
 962 9798 10512 0.9320 0.9596
MCF 10A SB590885
10
uM
LJP5
 72
hr
 962 6137 10512 0.5837 0.7108
MCF 10A Pictilisib
0.04
uM
LJP6
 72
hr
 962 10649 10692 0.9960 0.9975
MCF 10A Pictilisib
0.12
uM
LJP6
 72
hr
 962 9437 10692 0.8827 0.9292
MCF 10A Pictilisib
0.37
uM
LJP6
 72
hr
 962 7038 10692 0.6583 0.7732
MCF 10A Pictilisib
1.11
uM
LJP6
 72
hr
 962 4104 10692 0.3839 0.5182
MCF 10A Pictilisib
3.33
uM
LJP6
 72
hr
 962 2782 10692 0.2603 0.3569
MCF 10A Pictilisib
10
uM
LJP6
 72
hr
 962 1286 10692 0.1203 0.0870
MCF 10A PD184352
0.04
uM
LJP5
 72
hr
 962 5377 10512 0.5111 0.6457
MCF 10A PD184352
0.12
uM
LJP5
 72
hr
 962 4935 10512 0.4693 0.6056