LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dactolisib
3.33
uM
LJP5
 72
hr
 658 945 3933 0.2404 0.1505
Hs 578T Dactolisib
10
uM
LJP5
 72
hr
 658 971 3933 0.2468 0.1625
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 658 3835 3933 0.9749 0.9803
Hs 578T Alpelisib
0.12
uM
LJP5
 72
hr
 658 3517 3933 0.8941 0.9149
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 658 3351 3933 0.8521 0.8797
Hs 578T Alpelisib
1.11
uM
LJP5
 72
hr
 658 3168 3933 0.8056 0.8390
Hs 578T Alpelisib
3.33
uM
LJP5
 72
hr
 658 2892 3933 0.7352 0.7751
Hs 578T Alpelisib
10
uM
LJP5
 72
hr
 658 2213 3933 0.5626 0.5998
Hs 578T GDC-0980
0.04
uM
LJP5
 72
hr
 658 2318 3933 0.5895 0.6294
Hs 578T GDC-0980
0.12
uM
LJP5
 72
hr
 658 1738 3933 0.4418 0.4568
Hs 578T GDC-0980
0.37
uM
LJP5
 72
hr
 658 1379 3933 0.3507 0.3322
Hs 578T GDC-0980
1.11
uM
LJP5
 72
hr
 658 1212 3933 0.3082 0.2669
Hs 578T GDC-0980
3.33
uM
LJP5
 72
hr
 658 1128 3933 0.2870 0.2324
Hs 578T GDC-0980
10
uM
LJP5
 72
hr
 658 1051 3933 0.2673 0.1990
Hs 578T Mitoxantrone
0.04
uM
LJP5
 72
hr
 658 707 3933 0.1797 0.0275
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 658 605 3761 0.1609 -0.0336
Hs 578T Mitoxantrone
0.12
uM
LJP5
 72
hr
 658 628 3933 0.1598 -0.0184
Hs 578T Mitoxantrone
0.12
uM
LJP6
 72
hr
 658 602 3761 0.1603 -0.0351
Hs 578T Mitoxantrone
0.37
uM
LJP5
 72
hr
 658 491 3933 0.1249 -0.1073
Hs 578T Mitoxantrone
0.37
uM
LJP6
 72
hr
 658 535 3761 0.1423 -0.0796
Hs 578T Mitoxantrone
1.11
uM
LJP5
 72
hr
 658 276 3933 0.0702 -0.2865
Hs 578T Mitoxantrone
1.11
uM
LJP6
 72
hr
 658 287 3761 0.0762 -0.2818
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 658 154 3933 0.0392 -0.4301
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 658 147 3761 0.0393 -0.4481
Hs 578T Mitoxantrone
10
uM
LJP5
 72
hr
 658 25 3933 0.0064 -0.7202