LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A GSK1904529A
0.37
uM
LJP6
 72
hr
 962 8562 10692 0.8008 0.8761
MCF 10A GSK1904529A
1.11
uM
LJP6
 72
hr
 962 8010 10692 0.7492 0.8403
MCF 10A GSK1904529A
3.33
uM
LJP6
 72
hr
 962 8142 10692 0.7615 0.8490
MCF 10A GSK1904529A
10
uM
LJP6
 72
hr
 962 7685 10692 0.7188 0.8186
MCF 10A Linsitinib
0.04
uM
LJP5
 72
hr
 962 10729 10512 1.0209 1.0120
MCF 10A Linsitinib
0.12
uM
LJP5
 72
hr
 962 10395 10512 0.9892 0.9937
MCF 10A Linsitinib
0.37
uM
LJP5
 72
hr
 962 9986 10512 0.9501 0.9705
MCF 10A Linsitinib
1.11
uM
LJP5
 72
hr
 962 9492 10512 0.9033 0.9418
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 962 9064 10512 0.8625 0.9159
MCF 10A Linsitinib
10
uM
LJP5
 72
hr
 962 8613 10512 0.8197 0.8879
MCF 10A Ruxolitinib
0.04
uM
LJP5
 72
hr
 962 10310 10512 0.9808 0.9888
MCF 10A Ruxolitinib
0.12
uM
LJP5
 72
hr
 962 10299 10512 0.9798 0.9882
MCF 10A Ruxolitinib
0.37
uM
LJP5
 72
hr
 962 10167 10512 0.9673 0.9808
MCF 10A Ruxolitinib
1.11
uM
LJP5
 72
hr
 962 9887 10512 0.9407 0.9649
MCF 10A Ruxolitinib
3.33
uM
LJP5
 72
hr
 962 9673 10512 0.9206 0.9524
MCF 10A Ruxolitinib
10
uM
LJP5
 72
hr
 962 7375 10512 0.7018 0.8047
MCF 10A Momelotinib
0.04
uM
LJP5
 72
hr
 962 10172 10512 0.9679 0.9811
MCF 10A Momelotinib
0.12
uM
LJP5
 72
hr
 962 9634 10512 0.9168 0.9503
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 962 8778 10512 0.8352 0.8983
MCF 10A Momelotinib
1.11
uM
LJP5
 72
hr
 962 7297 10512 0.6944 0.7993
MCF 10A Momelotinib
3.33
uM
LJP5
 72
hr
 962 4396 10512 0.4184 0.5535
MCF 10A Momelotinib
10
uM
LJP5
 72
hr
 962 1247 10512 0.1187 0.0779
MCF 10A Fedratinib
0.04
uM
LJP5
 72
hr
 962 9927 10512 0.9446 0.9671
MCF 10A Fedratinib
0.12
uM
LJP5
 72
hr
 962 9510 10512 0.9048 0.9427
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 962 8912 10512 0.8478 0.9062