LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T TWS119
0.12
uM
LJP5
 72
hr
 658 3837 3933 0.9755 0.9808
Hs 578T TWS119
0.37
uM
LJP5
 72
hr
 658 3875 3933 0.9853 0.9884
Hs 578T TWS119
1.11
uM
LJP5
 72
hr
 658 3374 3933 0.8578 0.8844
Hs 578T TWS119
3.33
uM
LJP5
 72
hr
 658 2381 3933 0.6054 0.6464
Hs 578T TWS119
10
uM
LJP5
 72
hr
 658 606 3933 0.1540 -0.0320
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 658 3621 3933 0.9206 0.9369
Hs 578T PF477736
0.12
uM
LJP5
 72
hr
 658 2350 3933 0.5973 0.6367
Hs 578T PF477736
0.37
uM
LJP5
 72
hr
 658 759 3933 0.1931 0.0561
Hs 578T PF477736
1.11
uM
LJP5
 72
hr
 658 574 3933 0.1459 -0.0525
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 658 566 3933 0.1440 -0.0571
Hs 578T PF477736
10
uM
LJP5
 72
hr
 658 449 3933 0.1143 -0.1376
Hs 578T LDN-193189
0.04
uM
LJP5
 72
hr
 658 3797 3933 0.9654 0.9728
Hs 578T LDN-193189
0.12
uM
LJP5
 72
hr
 658 3456 3933 0.8788 0.9022
Hs 578T LDN-193189
0.37
uM
LJP5
 72
hr
 658 3304 3933 0.8400 0.8692
Hs 578T LDN-193189
1.11
uM
LJP5
 72
hr
 658 2927 3933 0.7440 0.7819
Hs 578T LDN-193189
3.33
uM
LJP5
 72
hr
 658 183 3933 0.0465 -0.3919
Hs 578T LDN-193189
10
uM
LJP5
 72
hr
 658 212 3933 0.0539 -0.3573
Hs 578T PF431396
0.04
uM
LJP5
 72
hr
 658 2917 3933 0.7415 0.7810
Hs 578T PF431396
0.12
uM
LJP5
 72
hr
 658 2663 3933 0.6771 0.7191
Hs 578T PF431396
0.37
uM
LJP5
 72
hr
 658 1815 3933 0.4614 0.4817
Hs 578T PF431396
1.11
uM
LJP5
 72
hr
 658 1163 3933 0.2958 0.2469
Hs 578T PF431396
3.33
uM
LJP5
 72
hr
 658 1070 3933 0.2721 0.2070
Hs 578T PF431396
10
uM
LJP5
 72
hr
 658 570 3933 0.1448 -0.0557
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 658 3892 3761 1.0349 1.0274
Hs 578T Celastrol
0.12
uM
LJP6
 72
hr
 658 4026 3761 1.0707 1.0551