LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WH-4-025
1.11
uM
LJP5
 72
hr
 658 528 3933 0.1342 -0.0822
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 658 460 3933 0.1170 -0.1307
Hs 578T WH-4-025
10
uM
LJP5
 72
hr
 658 186 3933 0.0473 -0.3913
Hs 578T R406
0.04
uM
LJP6
 72
hr
 658 3673 3761 0.9768 0.9814
Hs 578T R406
0.12
uM
LJP6
 72
hr
 658 3350 3761 0.8906 0.9097
Hs 578T R406
0.37
uM
LJP6
 72
hr
 658 3181 3761 0.8461 0.8714
Hs 578T R406
1.11
uM
LJP6
 72
hr
 658 2773 3761 0.7369 0.7705
Hs 578T R406
3.33
uM
LJP6
 72
hr
 658 1994 3761 0.5303 0.5539
Hs 578T R406
10
uM
LJP6
 72
hr
 658 984 3761 0.2618 0.1734
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 658 471 3761 0.1255 -0.1241
Hs 578T BI-2536
0.12
uM
LJP6
 72
hr
 658 493 3761 0.1311 -0.1087
Hs 578T BI-2536
0.37
uM
LJP6
 72
hr
 658 527 3761 0.1402 -0.0849
Hs 578T BI-2536
1.11
uM
LJP6
 72
hr
 658 578 3761 0.1538 -0.0503
Hs 578T BI-2536
3.33
uM
LJP6
 72
hr
 658 602 3761 0.1602 -0.0348
Hs 578T BI-2536
10
uM
LJP6
 72
hr
 658 455 3761 0.1209 -0.1387
Hs 578T A443654
0.04
uM
LJP6
 72
hr
 658 2140 3761 0.5693 0.5985
Hs 578T A443654
0.12
uM
LJP6
 72
hr
 658 940 3761 0.2502 0.1524
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 658 384 3761 0.1022 -0.1934
Hs 578T A443654
1.11
uM
LJP6
 72
hr
 658 308 3761 0.0819 -0.2618
Hs 578T A443654
3.33
uM
LJP6
 72
hr
 658 294 3761 0.0781 -0.2747
Hs 578T A443654
10
uM
LJP6
 72
hr
 658 258 3761 0.0686 -0.3111
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 658 4370 3933 1.1111 1.0833
Hs 578T SB590885
0.12
uM
LJP5
 72
hr
 658 4216 3933 1.0720 1.0547
Hs 578T SB590885
0.37
uM
LJP5
 72
hr
 658 4046 3933 1.0286 1.0220
Hs 578T SB590885
1.11
uM
LJP5
 72
hr
 658 4011 3933 1.0196 1.0151