LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T SB590885
3.33
uM
LJP5
 72
hr
 658 3895 3933 0.9903 0.9924
Hs 578T SB590885
10
uM
LJP5
 72
hr
 658 125 3933 0.0320 -0.4740
Hs 578T Pictilisib
0.04
uM
LJP6
 72
hr
 658 2954 3761 0.7852 0.8163
Hs 578T Pictilisib
0.12
uM
LJP6
 72
hr
 658 2505 3761 0.6660 0.7014
Hs 578T Pictilisib
0.37
uM
LJP6
 72
hr
 658 2388 3761 0.6353 0.6698
Hs 578T Pictilisib
1.11
uM
LJP6
 72
hr
 658 2100 3761 0.5585 0.5862
Hs 578T Pictilisib
3.33
uM
LJP6
 72
hr
 658 1874 3761 0.4984 0.5161
Hs 578T Pictilisib
10
uM
LJP6
 72
hr
 658 1333 3761 0.3545 0.3240
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 658 3334 3933 0.8477 0.8758
Hs 578T PD184352
0.12
uM
LJP5
 72
hr
 658 2986 3933 0.7594 0.7974
Hs 578T PD184352
0.37
uM
LJP5
 72
hr
 658 2747 3933 0.6984 0.7401
Hs 578T PD184352
1.11
uM
LJP5
 72
hr
 658 2468 3933 0.6275 0.6689
Hs 578T PD184352
3.33
uM
LJP5
 72
hr
 658 2159 3933 0.5490 0.5848
Hs 578T PD184352
10
uM
LJP5
 72
hr
 658 1158 3933 0.2944 0.2448
Hs 578T PLX-4720
0.04
uM
LJP5
 72
hr
 658 4035 3933 1.0257 1.0196
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 658 4140 3933 1.0527 1.0402
Hs 578T PLX-4720
0.37
uM
LJP5
 72
hr
 658 4100 3933 1.0425 1.0325
Hs 578T PLX-4720
1.11
uM
LJP5
 72
hr
 658 3899 3933 0.9915 0.9933
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 658 3690 3933 0.9381 0.9508
Hs 578T PLX-4720
10
uM
LJP5
 72
hr
 658 2868 3933 0.7290 0.7687
Hs 578T Lapatinib
0.04
uM
LJP6
 72
hr
 658 3543 3761 0.9421 0.9530
Hs 578T Lapatinib
0.12
uM
LJP6
 72
hr
 658 3677 3761 0.9779 0.9823
Hs 578T Lapatinib
0.37
uM
LJP6
 72
hr
 658 3714 3761 0.9876 0.9901
Hs 578T Lapatinib
1.11
uM
LJP6
 72
hr
 658 3746 3761 0.9962 0.9970
Hs 578T Lapatinib
3.33
uM
LJP6
 72
hr
 658 3908 3761 1.0391 1.0306