LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 PIK-93
0.04
uM
LJP5
 72
hr
 1097 3895 3846 1.0138 1.0156
BT-20 PIK-93
0.12
uM
LJP5
 72
hr
 1097 4017 3846 1.0449 1.0483
BT-20 PIK-93
0.37
uM
LJP5
 72
hr
 1097 3878 3846 1.0088 1.0095
BT-20 PIK-93
1.11
uM
LJP5
 72
hr
 1097 3501 3846 0.9101 0.8982
BT-20 PIK-93
3.33
uM
LJP5
 72
hr
 1097 3007 3846 0.7822 0.7462
BT-20 PIK-93
10
uM
LJP5
 72
hr
 1097 1361 3846 0.3541 0.1266
BT-20 Dactolisib
0.04
uM
LJP5
 72
hr
 1097 1392 3846 0.3624 0.1409
BT-20 Dactolisib
0.12
uM
LJP5
 72
hr
 1097 1098 3846 0.2860 0.0005
BT-20 Dactolisib
0.37
uM
LJP5
 72
hr
 1097 1053 3846 0.2743 -0.0220
BT-20 Dactolisib
1.11
uM
LJP5
 72
hr
 1097 1231 3846 0.3208 0.0656
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1097 1295 3846 0.3372 0.0961
BT-20 Dactolisib
10
uM
LJP5
 72
hr
 1097 1422 3846 0.3704 0.1543
BT-20 Alpelisib
0.04
uM
LJP5
 72
hr
 1097 4057 3846 1.0566 1.0607
BT-20 Alpelisib
0.12
uM
LJP5
 72
hr
 1097 3808 3846 0.9907 0.9892
BT-20 Alpelisib
0.37
uM
LJP5
 72
hr
 1097 2957 3846 0.7696 0.7279
BT-20 Alpelisib
1.11
uM
LJP5
 72
hr
 1097 2083 3846 0.5425 0.4257
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1097 1241 3846 0.3224 0.0683
BT-20 Alpelisib
10
uM
LJP5
 72
hr
 1097 758 3846 0.1971 -0.1852
BT-20 GDC-0980
0.04
uM
LJP5
 72
hr
 1097 1402 3846 0.3645 0.1439
BT-20 GDC-0980
0.12
uM
LJP5
 72
hr
 1097 984 3846 0.2560 -0.0584
BT-20 GDC-0980
0.37
uM
LJP5
 72
hr
 1097 868 3846 0.2260 -0.1211
BT-20 GDC-0980
1.11
uM
LJP5
 72
hr
 1097 832 3846 0.2163 -0.1421
BT-20 GDC-0980
3.33
uM
LJP5
 72
hr
 1097 785 3846 0.2043 -0.1691
BT-20 GDC-0980
10
uM
LJP5
 72
hr
 1097 754 3846 0.1962 -0.1874
BT-20 Mitoxantrone
0.04
uM
LJP5
 72
hr
 1097 1459 3846 0.3793 0.1699