LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Tozasertib
3.33
uM
LJP5
 72
hr
 962 1348 10512 0.1283 0.1025
MCF 10A Tozasertib
10
uM
LJP5
 72
hr
 962 1266 10512 0.1205 0.0828
MCF 10A Imatinib
0.04
uM
LJP6
 72
hr
 962 10713 10692 1.0020 1.0012
MCF 10A Imatinib
0.12
uM
LJP6
 72
hr
 962 10735 10692 1.0040 1.0023
MCF 10A Imatinib
0.37
uM
LJP6
 72
hr
 962 10628 10692 0.9941 0.9966
MCF 10A Imatinib
1.11
uM
LJP6
 72
hr
 962 10527 10692 0.9845 0.9910
MCF 10A Imatinib
3.33
uM
LJP6
 72
hr
 962 10598 10692 0.9912 0.9947
MCF 10A Imatinib
10
uM
LJP6
 72
hr
 962 10038 10692 0.9387 0.9637
MCF 10A NVP-TAE684
0.04
uM
LJP6
 72
hr
 962 9483 10692 0.8869 0.9320
MCF 10A NVP-TAE684
0.12
uM
LJP6
 72
hr
 962 8136 10692 0.7609 0.8486
MCF 10A NVP-TAE684
0.37
uM
LJP6
 72
hr
 962 7023 10692 0.6568 0.7719
MCF 10A NVP-TAE684
1.11
uM
LJP6
 72
hr
 962 5457 10692 0.5103 0.6440
MCF 10A NVP-TAE684
3.33
uM
LJP6
 72
hr
 962 4458 10692 0.4169 0.5517
MCF 10A NVP-TAE684
10
uM
LJP6
 72
hr
 962 1023 10692 0.0957 0.0177
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 962 4799 10512 0.4569 0.5925
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 962 400 10692 0.0375 -0.2234
MCF 10A CGP60474
0.12
uM
LJP5
 72
hr
 962 387 10512 0.0368 -0.2331
MCF 10A CGP60474
0.12
uM
LJP6
 72
hr
 962 253 10692 0.0237 -0.3195
MCF 10A CGP60474
0.37
uM
LJP5
 72
hr
 962 263 10512 0.0251 -0.3130
MCF 10A CGP60474
0.37
uM
LJP6
 72
hr
 962 277 10692 0.0260 -0.3019
MCF 10A CGP60474
1.11
uM
LJP5
 72
hr
 962 245 10512 0.0233 -0.3280
MCF 10A CGP60474
1.11
uM
LJP6
 72
hr
 962 236 10692 0.0221 -0.3323
MCF 10A CGP60474
3.33
uM
LJP5
 72
hr
 962 292 10512 0.0278 -0.2931
MCF 10A CGP60474
3.33
uM
LJP6
 72
hr
 962 238 10692 0.0223 -0.3328
MCF 10A CGP60474
10
uM
LJP5
 72
hr
 962 326 10512 0.0310 -0.2699