LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A AZD 5438
10
uM
LJP6
 72
hr
 962 333 10692 0.0312 -0.2640
MCF 10A Pelitinib
0.04
uM
LJP5
 72
hr
 962 3164 10512 0.3017 0.4102
MCF 10A Pelitinib
0.12
uM
LJP5
 72
hr
 962 1400 10512 0.1332 0.1149
MCF 10A Pelitinib
0.37
uM
LJP5
 72
hr
 962 1340 10512 0.1274 0.0997
MCF 10A Pelitinib
1.11
uM
LJP5
 72
hr
 962 1405 10512 0.1337 0.1159
MCF 10A Pelitinib
3.33
uM
LJP5
 72
hr
 962 1435 10512 0.1365 0.1225
MCF 10A Pelitinib
10
uM
LJP5
 72
hr
 962 752 10512 0.0716 -0.0690
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 962 834 10512 0.0793 -0.0407
MCF 10A Luminespib
0.12
uM
LJP5
 72
hr
 962 783 10512 0.0745 -0.0580
MCF 10A Luminespib
0.37
uM
LJP5
 72
hr
 962 826 10512 0.0787 -0.0433
MCF 10A Luminespib
1.11
uM
LJP5
 72
hr
 962 822 10512 0.0782 -0.0446
MCF 10A Luminespib
3.33
uM
LJP5
 72
hr
 962 816 10512 0.0777 -0.0466
MCF 10A Luminespib
10
uM
LJP5
 72
hr
 962 854 10512 0.0812 -0.0349
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 962 1546 10512 0.1471 0.1473
MCF 10A AZD8330
0.12
uM
LJP5
 72
hr
 962 1687 10512 0.1606 0.1765
MCF 10A AZD8330
0.37
uM
LJP5
 72
hr
 962 1613 10512 0.1535 0.1614
MCF 10A AZD8330
1.11
uM
LJP5
 72
hr
 962 1630 10512 0.1551 0.1650
MCF 10A AZD8330
3.33
uM
LJP5
 72
hr
 962 1724 10512 0.1641 0.1842
MCF 10A AZD8330
10
uM
LJP5
 72
hr
 962 1760 10512 0.1675 0.1913
MCF 10A TGX221
0.04
uM
LJP5
 72
hr
 962 10397 10512 0.9898 0.9937
MCF 10A TGX221
0.12
uM
LJP5
 72
hr
 962 10564 10512 1.0050 1.0029
MCF 10A TGX221
0.37
uM
LJP5
 72
hr
 962 10319 10512 0.9816 0.9892
MCF 10A TGX221
1.11
uM
LJP5
 72
hr
 962 10338 10512 0.9832 0.9900
MCF 10A TGX221
3.33
uM
LJP5
 72
hr
 962 10595 10512 1.0080 1.0044
MCF 10A TGX221
10
uM
LJP5
 72
hr
 962 10603 10512 1.0085 1.0048