LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A XL147
3.33
uM
LJP5
 72
hr
 962 7621 10512 0.7248 0.8217
MCF 10A XL147
10
uM
LJP5
 72
hr
 962 4368 10512 0.4155 0.5505
MCF 10A Y39983
0.04
uM
LJP6
 72
hr
 962 10258 10692 0.9595 0.9763
MCF 10A Y39983
0.12
uM
LJP6
 72
hr
 962 9910 10692 0.9268 0.9567
MCF 10A Y39983
0.37
uM
LJP6
 72
hr
 962 9470 10692 0.8858 0.9313
MCF 10A Y39983
1.11
uM
LJP6
 72
hr
 962 9214 10692 0.8619 0.9161
MCF 10A Y39983
3.33
uM
LJP6
 72
hr
 962 8878 10692 0.8304 0.8956
MCF 10A Y39983
10
uM
LJP6
 72
hr
 962 4273 10692 0.3999 0.5341
MCF 10A Nintedanib
0.04
uM
LJP6
 72
hr
 962 10963 10692 1.0254 1.0145
MCF 10A Nintedanib
0.12
uM
LJP6
 72
hr
 962 10709 10692 1.0016 1.0009
MCF 10A Nintedanib
0.37
uM
LJP6
 72
hr
 962 10620 10692 0.9932 0.9960
MCF 10A Nintedanib
1.11
uM
LJP6
 72
hr
 962 10613 10692 0.9927 0.9958
MCF 10A Nintedanib
3.33
uM
LJP6
 72
hr
 962 10662 10692 0.9972 0.9983
MCF 10A Nintedanib
10
uM
LJP6
 72
hr
 962 10394 10692 0.9722 0.9838
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 962 10370 10512 0.9865 0.9921
MCF 10A Foretinib
0.12
uM
LJP5
 72
hr
 962 9846 10512 0.9363 0.9621
MCF 10A Foretinib
0.37
uM
LJP5
 72
hr
 962 8386 10512 0.7977 0.8731
MCF 10A Foretinib
1.11
uM
LJP5
 72
hr
 962 2756 10512 0.2619 0.3555
MCF 10A Foretinib
3.33
uM
LJP5
 72
hr
 962 1490 10512 0.1417 0.1349
MCF 10A Foretinib
10
uM
LJP5
 72
hr
 962 930 10512 0.0886 -0.0098
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 962 9619 10692 0.8997 0.9401
MCF 10A AZD 5438
0.12
uM
LJP6
 72
hr
 962 7001 10692 0.6548 0.7702
MCF 10A AZD 5438
0.37
uM
LJP6
 72
hr
 962 2408 10692 0.2253 0.3018
MCF 10A AZD 5438
1.11
uM
LJP6
 72
hr
 962 710 10692 0.0665 -0.0843
MCF 10A AZD 5438
3.33
uM
LJP6
 72
hr
 962 260 10692 0.0244 -0.3138