LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Nilotinib
1.11
uM
LJP5
 72
hr
 962 9491 10512 0.9029 0.9417
MCF 10A Nilotinib
3.33
uM
LJP5
 72
hr
 962 9492 10512 0.9033 0.9418
MCF 10A Nilotinib
10
uM
LJP5
 72
hr
 962 2718 10512 0.2590 0.3503
MCF 10A JNK-9L
0.04
uM
LJP6
 72
hr
 962 10851 10692 1.0149 1.0085
MCF 10A JNK-9L
0.12
uM
LJP6
 72
hr
 962 9821 10692 0.9186 0.9517
MCF 10A JNK-9L
0.37
uM
LJP6
 72
hr
 962 5911 10692 0.5529 0.6861
MCF 10A JNK-9L
1.11
uM
LJP6
 72
hr
 962 926 10692 0.0867 -0.0113
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 962 460 10692 0.0431 -0.1928
MCF 10A JNK-9L
10
uM
LJP6
 72
hr
 962 722 10692 0.0676 -0.0801
MCF 10A PD0325901
0.04
uM
LJP5
 72
hr
 962 2600 10512 0.2473 0.3314
MCF 10A PD0325901
0.04
uM
LJP6
 72
hr
 962 2212 10692 0.2070 0.2700
MCF 10A PD0325901
0.12
uM
LJP5
 72
hr
 962 1928 10512 0.1833 0.2228
MCF 10A PD0325901
0.12
uM
LJP6
 72
hr
 962 1884 10692 0.1762 0.2134
MCF 10A PD0325901
0.37
uM
LJP5
 72
hr
 962 1826 10512 0.1738 0.2041
MCF 10A PD0325901
0.37
uM
LJP6
 72
hr
 962 1707 10692 0.1597 0.1791
MCF 10A PD0325901
1.11
uM
LJP5
 72
hr
 962 1810 10512 0.1721 0.2003
MCF 10A PD0325901
1.11
uM
LJP6
 72
hr
 962 1369 10692 0.1281 0.1065
MCF 10A PD0325901
3.33
uM
LJP5
 72
hr
 962 1867 10512 0.1779 0.2103
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 962 1133 10692 0.1060 0.0479
MCF 10A PD0325901
10
uM
LJP5
 72
hr
 962 1600 10512 0.1524 0.1589
MCF 10A PD0325901
10
uM
LJP6
 72
hr
 962 1137 10692 0.1063 0.0488
MCF 10A Geldanamycin
0.04
uM
LJP5
 72
hr
 962 1729 10512 0.1645 0.1850
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 962 1229 10692 0.1150 0.0729
MCF 10A Geldanamycin
0.12
uM
LJP5
 72
hr
 962 1004 10512 0.0956 0.0121
MCF 10A Geldanamycin
0.12
uM
LJP6
 72
hr
 962 786 10692 0.0736 -0.0569