LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A CGP60474
10
uM
LJP6
 72
hr
 962 279 10692 0.0261 -0.2996
MCF 10A PD173074
0.04
uM
LJP6
 72
hr
 962 11072 10692 1.0356 1.0202
MCF 10A PD173074
0.12
uM
LJP6
 72
hr
 962 10757 10692 1.0062 1.0035
MCF 10A PD173074
0.37
uM
LJP6
 72
hr
 962 10653 10692 0.9964 0.9979
MCF 10A PD173074
1.11
uM
LJP6
 72
hr
 962 10573 10692 0.9889 0.9935
MCF 10A PD173074
3.33
uM
LJP6
 72
hr
 962 10254 10692 0.9590 0.9761
MCF 10A PD173074
10
uM
LJP6
 72
hr
 962 7264 10692 0.6794 0.7894
MCF 10A Crizotinib
0.04
uM
LJP5
 72
hr
 962 10700 10512 1.0181 1.0104
MCF 10A Crizotinib
0.12
uM
LJP5
 72
hr
 962 10435 10512 0.9927 0.9958
MCF 10A Crizotinib
0.37
uM
LJP5
 72
hr
 962 9789 10512 0.9313 0.9591
MCF 10A Crizotinib
1.11
uM
LJP5
 72
hr
 962 9096 10512 0.8654 0.9179
MCF 10A Crizotinib
3.33
uM
LJP5
 72
hr
 962 7981 10512 0.7593 0.8464
MCF 10A Crizotinib
10
uM
LJP5
 72
hr
 962 1392 10512 0.1326 0.1130
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 962 10478 10692 0.9800 0.9884
MCF 10A BMS345541
0.12
uM
LJP6
 72
hr
 962 10223 10692 0.9561 0.9742
MCF 10A BMS345541
0.37
uM
LJP6
 72
hr
 962 10337 10692 0.9668 0.9806
MCF 10A BMS345541
1.11
uM
LJP6
 72
hr
 962 10222 10692 0.9561 0.9742
MCF 10A BMS345541
3.33
uM
LJP6
 72
hr
 962 10231 10692 0.9569 0.9748
MCF 10A BMS345541
10
uM
LJP6
 72
hr
 962 8900 10692 0.8324 0.8970
MCF 10A KIN001-043
0.04
uM
LJP6
 72
hr
 962 9995 10692 0.9349 0.9613
MCF 10A KIN001-043
0.12
uM
LJP6
 72
hr
 962 9752 10692 0.9123 0.9475
MCF 10A KIN001-043
0.37
uM
LJP6
 72
hr
 962 9883 10692 0.9245 0.9553
MCF 10A KIN001-043
1.11
uM
LJP6
 72
hr
 962 9860 10692 0.9222 0.9539
MCF 10A KIN001-043
3.33
uM
LJP6
 72
hr
 962 8700 10692 0.8138 0.8846
MCF 10A KIN001-043
10
uM
LJP6
 72
hr
 962 4948 10692 0.4630 0.6007