LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Foretinib
0.12
uM
LJP5
 72
hr
 658 3153 3933 0.8017 0.8356
Hs 578T Foretinib
0.37
uM
LJP5
 72
hr
 658 1285 3933 0.3269 0.2963
Hs 578T Foretinib
1.11
uM
LJP5
 72
hr
 658 1208 3933 0.3073 0.2656
Hs 578T Foretinib
3.33
uM
LJP5
 72
hr
 658 1085 3933 0.2759 0.2137
Hs 578T Foretinib
10
uM
LJP5
 72
hr
 658 431 3933 0.1097 -0.1531
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 658 3192 3761 0.8483 0.8728
Hs 578T AZD 5438
0.12
uM
LJP6
 72
hr
 658 2189 3761 0.5819 0.6120
Hs 578T AZD 5438
0.37
uM
LJP6
 72
hr
 658 1037 3761 0.2756 0.1968
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 658 562 3761 0.1496 -0.0609
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 658 446 3761 0.1188 -0.1431
Hs 578T AZD 5438
10
uM
LJP6
 72
hr
 658 383 3761 0.1019 -0.1944
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 658 3894 3933 0.9899 0.9921
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 658 3425 3933 0.8707 0.8954
Hs 578T Pelitinib
0.37
uM
LJP5
 72
hr
 658 3030 3933 0.7703 0.8075
Hs 578T Pelitinib
1.11
uM
LJP5
 72
hr
 658 3026 3933 0.7693 0.8065
Hs 578T Pelitinib
3.33
uM
LJP5
 72
hr
 658 1123 3933 0.2855 0.2280
Hs 578T Pelitinib
10
uM
LJP5
 72
hr
 658 448 3933 0.1141 -0.1393
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 658 771 3933 0.1961 0.0634
Hs 578T Luminespib
0.12
uM
LJP5
 72
hr
 658 781 3933 0.1986 0.0687
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 658 769 3933 0.1956 0.0624
Hs 578T Luminespib
1.11
uM
LJP5
 72
hr
 658 741 3933 0.1885 0.0472
Hs 578T Luminespib
3.33
uM
LJP5
 72
hr
 658 731 3933 0.1860 0.0413
Hs 578T Luminespib
10
uM
LJP5
 72
hr
 658 709 3933 0.1803 0.0293
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 658 1041 3933 0.2646 0.1939
Hs 578T AZD8330
0.12
uM
LJP5
 72
hr
 658 989 3933 0.2514 0.1710