LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Buparlisib
0.04
uM
LJP5
 72
hr
 658 3642 3933 0.9260 0.9411
Hs 578T Buparlisib
0.12
uM
LJP5
 72
hr
 658 3174 3933 0.8068 0.8402
Hs 578T Buparlisib
0.37
uM
LJP5
 72
hr
 658 2458 3933 0.6250 0.6667
Hs 578T Buparlisib
1.11
uM
LJP5
 72
hr
 658 1105 3933 0.2809 0.2219
Hs 578T Buparlisib
3.33
uM
LJP5
 72
hr
 658 477 3933 0.1213 -0.1177
Hs 578T Buparlisib
10
uM
LJP5
 72
hr
 658 395 3933 0.1006 -0.1794
Hs 578T XL147
0.04
uM
LJP5
 72
hr
 658 3992 3933 1.0150 1.0115
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 658 3947 3933 1.0034 1.0026
Hs 578T XL147
0.37
uM
LJP5
 72
hr
 658 3928 3933 0.9987 0.9990
Hs 578T XL147
1.11
uM
LJP5
 72
hr
 658 3843 3933 0.9771 0.9818
Hs 578T XL147
3.33
uM
LJP5
 72
hr
 658 3861 3933 0.9816 0.9856
Hs 578T XL147
10
uM
LJP5
 72
hr
 658 3179 3933 0.8082 0.8413
Hs 578T Y39983
0.04
uM
LJP6
 72
hr
 658 3164 3761 0.8415 0.8673
Hs 578T Y39983
0.12
uM
LJP6
 72
hr
 658 3239 3761 0.8614 0.8846
Hs 578T Y39983
0.37
uM
LJP6
 72
hr
 658 3036 3761 0.8071 0.8362
Hs 578T Y39983
1.11
uM
LJP6
 72
hr
 658 2905 3761 0.7726 0.8048
Hs 578T Y39983
3.33
uM
LJP6
 72
hr
 658 2439 3761 0.6487 0.6838
Hs 578T Y39983
10
uM
LJP6
 72
hr
 658 567 3761 0.1510 -0.0578
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 658 3556 3761 0.9453 0.9552
Hs 578T Nintedanib
0.12
uM
LJP6
 72
hr
 658 3394 3761 0.9024 0.9198
Hs 578T Nintedanib
0.37
uM
LJP6
 72
hr
 658 2819 3761 0.7495 0.7830
Hs 578T Nintedanib
1.11
uM
LJP6
 72
hr
 658 2320 3761 0.6167 0.6497
Hs 578T Nintedanib
3.33
uM
LJP6
 72
hr
 658 1722 3761 0.4580 0.4659
Hs 578T Nintedanib
10
uM
LJP6
 72
hr
 658 684 3761 0.1819 0.0154
Hs 578T Foretinib
0.04
uM
LJP5
 72
hr
 658 3843 3933 0.9772 0.9821