LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF 10A Linifanib
0.12
uM
LJP6
 72
hr
 962 11286 10692 1.0556 1.0314
MCF 10A Linifanib
0.37
uM
LJP6
 72
hr
 962 11407 10692 1.0669 1.0376
MCF 10A Linifanib
1.11
uM
LJP6
 72
hr
 962 11416 10692 1.0678 1.0381
MCF 10A Linifanib
3.33
uM
LJP6
 72
hr
 962 11160 10692 1.0438 1.0248
MCF 10A Linifanib
10
uM
LJP6
 72
hr
 962 7918 10692 0.7407 0.8344
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 962 10362 10512 0.9857 0.9916
MCF 10A PIK-93
0.12
uM
LJP5
 72
hr
 962 10035 10512 0.9544 0.9729
MCF 10A PIK-93
0.37
uM
LJP5
 72
hr
 962 9823 10512 0.9347 0.9610
MCF 10A PIK-93
1.11
uM
LJP5
 72
hr
 962 9343 10512 0.8888 0.9325
MCF 10A PIK-93
3.33
uM
LJP5
 72
hr
 962 8566 10512 0.8148 0.8842
MCF 10A PIK-93
10
uM
LJP5
 72
hr
 962 4397 10512 0.4183 0.5524
MCF 10A Dactolisib
0.04
uM
LJP5
 72
hr
 962 1625 10512 0.1546 0.1640
MCF 10A Dactolisib
0.12
uM
LJP5
 72
hr
 962 1537 10512 0.1461 0.1444
MCF 10A Dactolisib
0.37
uM
LJP5
 72
hr
 962 1556 10512 0.1480 0.1492
MCF 10A Dactolisib
1.11
uM
LJP5
 72
hr
 962 1409 10512 0.1341 0.1169
MCF 10A Dactolisib
3.33
uM
LJP5
 72
hr
 962 1436 10512 0.1367 0.1225
MCF 10A Dactolisib
10
uM
LJP5
 72
hr
 962 1653 10512 0.1573 0.1698
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 962 10528 10512 1.0015 1.0007
MCF 10A Alpelisib
0.12
uM
LJP5
 72
hr
 962 10278 10512 0.9779 0.9870
MCF 10A Alpelisib
0.37
uM
LJP5
 72
hr
 962 9803 10512 0.9326 0.9600
MCF 10A Alpelisib
1.11
uM
LJP5
 72
hr
 962 9137 10512 0.8695 0.9205
MCF 10A Alpelisib
3.33
uM
LJP5
 72
hr
 962 8262 10512 0.7859 0.8649
MCF 10A Alpelisib
10
uM
LJP5
 72
hr
 962 4539 10512 0.4318 0.5674
MCF 10A GDC-0980
0.04
uM
LJP5
 72
hr
 962 8572 10512 0.8152 0.8848
MCF 10A GDC-0980
0.12
uM
LJP5
 72
hr
 962 4274 10512 0.4065 0.5400