LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 658 567 3933 0.1442 -0.0560
Hs 578T Dasatinib
1.11
uM
LJP6
 72
hr
 658 574 3761 0.1529 -0.0538
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 658 556 3933 0.1414 -0.0638
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 658 540 3761 0.1437 -0.0755
Hs 578T Dasatinib
10
uM
LJP5
 72
hr
 658 608 3933 0.1547 -0.0325
Hs 578T Dasatinib
10
uM
LJP6
 72
hr
 658 436 3761 0.1159 -0.1512
Hs 578T Tozasertib
0.04
uM
LJP5
 72
hr
 658 779 3933 0.1981 0.0675
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 658 764 3933 0.1943 0.0592
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 658 789 3933 0.2006 0.0727
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 658 716 3933 0.1820 0.0327
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 658 791 3933 0.2012 0.0734
Hs 578T Tozasertib
10
uM
LJP5
 72
hr
 658 786 3933 0.1998 0.0712
Hs 578T Imatinib
0.04
uM
LJP6
 72
hr
 658 3808 3761 1.0127 1.0099
Hs 578T Imatinib
0.12
uM
LJP6
 72
hr
 658 3710 3761 0.9865 0.9892
Hs 578T Imatinib
0.37
uM
LJP6
 72
hr
 658 3634 3761 0.9665 0.9729
Hs 578T Imatinib
1.11
uM
LJP6
 72
hr
 658 3672 3761 0.9764 0.9811
Hs 578T Imatinib
3.33
uM
LJP6
 72
hr
 658 3729 3761 0.9915 0.9930
Hs 578T Imatinib
10
uM
LJP6
 72
hr
 658 3447 3761 0.9161 0.9310
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 658 3080 3761 0.8188 0.8470
Hs 578T NVP-TAE684
0.12
uM
LJP6
 72
hr
 658 2583 3761 0.6867 0.7222
Hs 578T NVP-TAE684
0.37
uM
LJP6
 72
hr
 658 1913 3761 0.5085 0.5282
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 658 1122 3761 0.2987 0.2319
Hs 578T NVP-TAE684
3.33
uM
LJP6
 72
hr
 658 832 3761 0.2213 0.0978
Hs 578T NVP-TAE684
10
uM
LJP6
 72
hr
 658 210 3761 0.0561 -0.3648
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 658 2861 3933 0.7273 0.7675