LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T CGP60474
0.04
uM
LJP6
 72
hr
 658 524 3761 0.1395 -0.0863
Hs 578T CGP60474
0.12
uM
LJP5
 72
hr
 658 683 3933 0.1738 0.0140
Hs 578T CGP60474
0.12
uM
LJP6
 72
hr
 658 468 3761 0.1244 -0.1276
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 658 456 3933 0.1159 -0.1327
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 658 517 3761 0.1374 -0.0920
Hs 578T CGP60474
1.11
uM
LJP5
 72
hr
 658 435 3933 0.1107 -0.1485
Hs 578T CGP60474
1.11
uM
LJP6
 72
hr
 658 461 3761 0.1227 -0.1325
Hs 578T CGP60474
3.33
uM
LJP5
 72
hr
 658 383 3933 0.0975 -0.1895
Hs 578T CGP60474
3.33
uM
LJP6
 72
hr
 658 440 3761 0.1170 -0.1480
Hs 578T CGP60474
10
uM
LJP5
 72
hr
 658 366 3933 0.0932 -0.2032
Hs 578T CGP60474
10
uM
LJP6
 72
hr
 658 379 3761 0.1008 -0.1986
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 658 3362 3761 0.8942 0.9130
Hs 578T PD173074
0.12
uM
LJP6
 72
hr
 658 3209 3761 0.8533 0.8776
Hs 578T PD173074
0.37
uM
LJP6
 72
hr
 658 3211 3761 0.8540 0.8784
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 658 3185 3761 0.8469 0.8719
Hs 578T PD173074
3.33
uM
LJP6
 72
hr
 658 2923 3761 0.7774 0.8094
Hs 578T PD173074
10
uM
LJP6
 72
hr
 658 897 3761 0.2387 0.1310
Hs 578T Crizotinib
0.04
uM
LJP5
 72
hr
 658 3661 3933 0.9308 0.9451
Hs 578T Crizotinib
0.12
uM
LJP5
 72
hr
 658 3527 3933 0.8967 0.9172
Hs 578T Crizotinib
0.37
uM
LJP5
 72
hr
 658 3387 3933 0.8611 0.8871
Hs 578T Crizotinib
1.11
uM
LJP5
 72
hr
 658 2349 3933 0.5971 0.6371
Hs 578T Crizotinib
3.33
uM
LJP5
 72
hr
 658 934 3933 0.2376 0.1454
Hs 578T Crizotinib
10
uM
LJP5
 72
hr
 658 867 3933 0.2206 0.1130
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 658 3909 3761 1.0394 1.0309
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 658 3764 3761 1.0006 1.0002