LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Erlotinib
10
uM
LJP5
 72
hr
 658 2420 3933 0.6154 0.6567
Hs 578T Gefitinib
0.04
uM
LJP6
 72
hr
 658 3776 3761 1.0039 1.0028
Hs 578T Gefitinib
0.12
uM
LJP6
 72
hr
 658 3688 3761 0.9809 0.9847
Hs 578T Gefitinib
0.37
uM
LJP6
 72
hr
 658 3769 3761 1.0024 1.0019
Hs 578T Gefitinib
1.11
uM
LJP6
 72
hr
 658 3741 3761 0.9948 0.9959
Hs 578T Gefitinib
3.33
uM
LJP6
 72
hr
 658 3709 3761 0.9864 0.9891
Hs 578T Gefitinib
10
uM
LJP6
 72
hr
 658 3123 3761 0.8305 0.8575
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 658 4075 3933 1.0362 1.0277
Hs 578T Nilotinib
0.12
uM
LJP5
 72
hr
 658 4002 3933 1.0174 1.0133
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 658 3952 3933 1.0048 1.0036
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 658 3961 3933 1.0071 1.0055
Hs 578T Nilotinib
3.33
uM
LJP5
 72
hr
 658 3771 3933 0.9587 0.9674
Hs 578T Nilotinib
10
uM
LJP5
 72
hr
 658 708 3933 0.1800 0.0279
Hs 578T JNK-9L
0.04
uM
LJP6
 72
hr
 658 3589 3761 0.9545 0.9632
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 658 3641 3761 0.9678 0.9738
Hs 578T JNK-9L
0.37
uM
LJP6
 72
hr
 658 2984 3761 0.7937 0.8243
Hs 578T JNK-9L
1.11
uM
LJP6
 72
hr
 658 1316 3761 0.3501 0.3160
Hs 578T JNK-9L
3.33
uM
LJP6
 72
hr
 658 494 3761 0.1313 -0.1082
Hs 578T JNK-9L
10
uM
LJP6
 72
hr
 658 506 3761 0.1346 -0.0995
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 658 2312 3933 0.5879 0.6276
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 658 2223 3761 0.5912 0.6226
Hs 578T PD0325901
0.12
uM
LJP5
 72
hr
 658 1727 3933 0.4391 0.4535
Hs 578T PD0325901
0.12
uM
LJP6
 72
hr
 658 1775 3761 0.4720 0.4837
Hs 578T PD0325901
0.37
uM
LJP5
 72
hr
 658 1357 3933 0.3451 0.3239
Hs 578T PD0325901
0.37
uM
LJP6
 72
hr
 658 1311 3761 0.3486 0.3151