LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T WZ3105
3.33
uM
LJP5
 72
hr
 658 469 3933 0.1194 -0.1232
Hs 578T WZ3105
10
uM
LJP5
 72
hr
 658 454 3933 0.1154 -0.1342
Hs 578T XMD11-50
0.04
uM
LJP6
 72
hr
 658 3410 3761 0.9068 0.9237
Hs 578T XMD11-50
0.12
uM
LJP6
 72
hr
 658 3109 3761 0.8267 0.8543
Hs 578T XMD11-50
0.37
uM
LJP6
 72
hr
 658 2800 3761 0.7447 0.7787
Hs 578T XMD11-50
1.11
uM
LJP6
 72
hr
 658 2353 3761 0.6257 0.6595
Hs 578T XMD11-50
3.33
uM
LJP6
 72
hr
 658 1683 3761 0.4476 0.4522
Hs 578T XMD11-50
10
uM
LJP6
 72
hr
 658 616 3761 0.1639 -0.0259
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 658 3506 3761 0.9321 0.9448
Hs 578T XMD11-85h
0.12
uM
LJP6
 72
hr
 658 3392 3761 0.9020 0.9196
Hs 578T XMD11-85h
0.37
uM
LJP6
 72
hr
 658 3316 3761 0.8819 0.9024
Hs 578T XMD11-85h
1.11
uM
LJP6
 72
hr
 658 3405 3761 0.9053 0.9224
Hs 578T XMD11-85h
3.33
uM
LJP6
 72
hr
 658 3049 3761 0.8107 0.8399
Hs 578T XMD11-85h
10
uM
LJP6
 72
hr
 658 1044 3761 0.2775 0.2005
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 658 797 3933 0.2028 0.0772
Hs 578T XMD16-144
0.12
uM
LJP5
 72
hr
 658 770 3933 0.1959 0.0627
Hs 578T XMD16-144
0.37
uM
LJP5
 72
hr
 658 778 3933 0.1978 0.0670
Hs 578T XMD16-144
1.11
uM
LJP5
 72
hr
 658 705 3933 0.1793 0.0271
Hs 578T XMD16-144
3.33
uM
LJP5
 72
hr
 658 605 3933 0.1539 -0.0323
Hs 578T XMD16-144
10
uM
LJP5
 72
hr
 658 484 3933 0.1231 -0.1125
Hs 578T Erlotinib
0.04
uM
LJP5
 72
hr
 658 3741 3933 0.9511 0.9613
Hs 578T Erlotinib
0.12
uM
LJP5
 72
hr
 658 3750 3933 0.9536 0.9634
Hs 578T Erlotinib
0.37
uM
LJP5
 72
hr
 658 3756 3933 0.9548 0.9643
Hs 578T Erlotinib
1.11
uM
LJP5
 72
hr
 658 3767 3933 0.9577 0.9668
Hs 578T Erlotinib
3.33
uM
LJP5
 72
hr
 658 3616 3933 0.9192 0.9357