LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset - HMS LINCS Database

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Small molecules	Cells

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	LJP Library Plate	Timepoint	Timepoint Unit	Mean Total Cell Count Before Treatment	Mean Total Cell Count After Treatment	Mean Total Control Cell Count	Mean Relative Cell Count	Mean Normalized Growth Rate Inhibition Value
BT-20	Trametinib	0.37	uM	LJP5	72	hr	1097	2861	3846	0.7446	0.6991
BT-20	Trametinib	1.11	uM	LJP5	72	hr	1097	2759	3846	0.7169	0.6629
BT-20	Trametinib	3.33	uM	LJP5	72	hr	1097	2749	3846	0.7154	0.6618
BT-20	Trametinib	10	uM	LJP5	72	hr	1097	2916	3846	0.7579	0.7152
BT-20	Omipalisib	0.04	uM	LJP6	72	hr	1097	778	3673	0.2117	-0.1793
BT-20	Omipalisib	0.12	uM	LJP6	72	hr	1097	729	3673	0.1986	-0.2091
BT-20	Omipalisib	0.37	uM	LJP6	72	hr	1097	608	3673	0.1658	-0.2869
BT-20	Omipalisib	1.11	uM	LJP6	72	hr	1097	512	3673	0.1395	-0.3543
BT-20	Omipalisib	3.33	uM	LJP6	72	hr	1097	491	3673	0.1338	-0.3691
BT-20	Omipalisib	10	uM	LJP6	72	hr	1097	428	3673	0.1164	-0.4180
BT-20	Buparlisib	0.04	uM	LJP5	72	hr	1097	3777	3846	0.9825	0.9802
BT-20	Buparlisib	0.12	uM	LJP5	72	hr	1097	3018	3846	0.7846	0.7486
BT-20	Buparlisib	0.37	uM	LJP5	72	hr	1097	1950	3846	0.5070	0.3734
BT-20	Buparlisib	1.11	uM	LJP5	72	hr	1097	1147	3846	0.2987	0.0251
BT-20	Buparlisib	3.33	uM	LJP5	72	hr	1097	732	3846	0.1905	-0.2004
BT-20	Buparlisib	10	uM	LJP5	72	hr	1097	621	3846	0.1617	-0.2699
BT-20	XL147	0.04	uM	LJP5	72	hr	1097	4302	3846	1.1181	1.1267
BT-20	XL147	0.12	uM	LJP5	72	hr	1097	4280	3846	1.1141	1.1232
BT-20	XL147	0.37	uM	LJP5	72	hr	1097	4153	3846	1.0804	1.0876
BT-20	XL147	1.11	uM	LJP5	72	hr	1097	3959	3846	1.0299	1.0332
BT-20	XL147	3.33	uM	LJP5	72	hr	1097	3318	3846	0.8626	0.8426
BT-20	XL147	10	uM	LJP5	72	hr	1097	1580	3846	0.4110	0.2230
BT-20	Y39983	0.04	uM	LJP6	72	hr	1097	3422	3673	0.9317	0.9202
BT-20	Y39983	0.12	uM	LJP6	72	hr	1097	3444	3673	0.9378	0.9277
BT-20	Y39983	0.37	uM	LJP6	72	hr	1097	3468	3673	0.9439	0.9344

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HMS LINCS Project

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)