LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
BT-20 Linsitinib
0.12
uM
LJP5
 72
hr
 1097 3616 3846 0.9402 0.9324
BT-20 Linsitinib
0.37
uM
LJP5
 72
hr
 1097 3689 3846 0.9601 0.9557
BT-20 Linsitinib
1.11
uM
LJP5
 72
hr
 1097 3603 3846 0.9379 0.9302
BT-20 Linsitinib
3.33
uM
LJP5
 72
hr
 1097 3521 3846 0.9169 0.9061
BT-20 Linsitinib
10
uM
LJP5
 72
hr
 1097 3196 3846 0.8311 0.8057
BT-20 Ruxolitinib
0.04
uM
LJP5
 72
hr
 1097 3687 3846 0.9587 0.9532
BT-20 Ruxolitinib
0.12
uM
LJP5
 72
hr
 1097 3629 3846 0.9443 0.9380
BT-20 Ruxolitinib
0.37
uM
LJP5
 72
hr
 1097 3655 3846 0.9513 0.9458
BT-20 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1097 4001 3846 1.0410 1.0453
BT-20 Ruxolitinib
3.33
uM
LJP5
 72
hr
 1097 3857 3846 1.0036 1.0043
BT-20 Ruxolitinib
10
uM
LJP5
 72
hr
 1097 3148 3846 0.8187 0.7908
BT-20 Momelotinib
0.04
uM
LJP5
 72
hr
 1097 3659 3846 0.9506 0.9431
BT-20 Momelotinib
0.12
uM
LJP5
 72
hr
 1097 3476 3846 0.9037 0.8895
BT-20 Momelotinib
0.37
uM
LJP5
 72
hr
 1097 3474 3846 0.9027 0.8888
BT-20 Momelotinib
1.11
uM
LJP5
 72
hr
 1097 3047 3846 0.7919 0.7575
BT-20 Momelotinib
3.33
uM
LJP5
 72
hr
 1097 2330 3846 0.6055 0.5135
BT-20 Momelotinib
10
uM
LJP5
 72
hr
 1097 1062 3846 0.2760 -0.0186
BT-20 Fedratinib
0.04
uM
LJP5
 72
hr
 1097 4106 3846 1.0684 1.0748
BT-20 Fedratinib
0.12
uM
LJP5
 72
hr
 1097 3770 3846 0.9815 0.9796
BT-20 Fedratinib
0.37
uM
LJP5
 72
hr
 1097 3539 3846 0.9208 0.9110
BT-20 Fedratinib
1.11
uM
LJP5
 72
hr
 1097 3146 3846 0.8182 0.7901
BT-20 Fedratinib
3.33
uM
LJP5
 72
hr
 1097 2597 3846 0.6757 0.6103
BT-20 Fedratinib
10
uM
LJP5
 72
hr
 1097 756 3846 0.1968 -0.1863
BT-20 Trametinib
0.04
uM
LJP5
 72
hr
 1097 3045 3846 0.7907 0.7546
BT-20 Trametinib
0.12
uM
LJP5
 72
hr
 1097 3041 3846 0.7906 0.7562