LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 13 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 3. - Dataset (ID:20250)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T HG-5-88-01
10
uM
LJP6
 72
hr
 658 2287 3761 0.6080 0.6407
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 658 3284 3761 0.8733 0.8949
Hs 578T HG-6-64-01
0.12
uM
LJP6
 72
hr
 658 2417 3761 0.6427 0.6775
Hs 578T HG-6-64-01
0.37
uM
LJP6
 72
hr
 658 1542 3761 0.4100 0.4026
Hs 578T HG-6-64-01
1.11
uM
LJP6
 72
hr
 658 963 3761 0.2562 0.1635
Hs 578T HG-6-64-01
3.33
uM
LJP6
 72
hr
 658 576 3761 0.1532 -0.0521
Hs 578T HG-6-64-01
10
uM
LJP6
 72
hr
 658 184 3761 0.0492 -0.3976
Hs 578T Neratinib
0.04
uM
LJP5
 72
hr
 658 3377 3933 0.8584 0.8845
Hs 578T Neratinib
0.12
uM
LJP5
 72
hr
 658 2999 3933 0.7625 0.8003
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 658 2043 3933 0.5193 0.5511
Hs 578T Neratinib
1.11
uM
LJP5
 72
hr
 658 1178 3933 0.2994 0.2518
Hs 578T Neratinib
3.33
uM
LJP5
 72
hr
 658 658 3933 0.1675 0.0000
Hs 578T Neratinib
10
uM
LJP5
 72
hr
 658 568 3933 0.1445 -0.0559
Hs 578T JW-7-24-1
0.04
uM
LJP6
 72
hr
 658 3349 3761 0.8904 0.9095
Hs 578T JW-7-24-1
0.12
uM
LJP6
 72
hr
 658 3068 3761 0.8158 0.8445
Hs 578T JW-7-24-1
0.37
uM
LJP6
 72
hr
 658 2601 3761 0.6913 0.7261
Hs 578T JW-7-24-1
1.11
uM
LJP6
 72
hr
 658 2001 3761 0.5319 0.5558
Hs 578T JW-7-24-1
3.33
uM
LJP6
 72
hr
 658 1400 3761 0.3724 0.3492
Hs 578T JW-7-24-1
10
uM
LJP6
 72
hr
 658 280 3761 0.0746 -0.2886
Hs 578T Dasatinib
0.04
uM
LJP5
 72
hr
 658 2521 3933 0.6408 0.6829
Hs 578T Dasatinib
0.04
uM
LJP6
 72
hr
 658 694 3761 0.1848 0.0215
Hs 578T Dasatinib
0.12
uM
LJP5
 72
hr
 658 1468 3933 0.3732 0.3645
Hs 578T Dasatinib
0.12
uM
LJP6
 72
hr
 658 708 3761 0.1885 0.0294
Hs 578T Dasatinib
0.37
uM
LJP5
 72
hr
 658 833 3933 0.2117 0.0945
Hs 578T Dasatinib
0.37
uM
LJP6
 72
hr
 658 668 3761 0.1775 0.0049