LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 765 501 3148 0.1592 -0.1876
Hs 578T Dasatinib
1.11
uM
LJP6
 72
hr
 765 511 3101 0.1648 -0.1810
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 765 482 3148 0.1531 -0.2040
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 765 416 3101 0.1344 -0.2603
Hs 578T Dasatinib
10
uM
LJP5
 72
hr
 765 480 3148 0.1526 -0.2040
Hs 578T Dasatinib
10
uM
LJP6
 72
hr
 765 354 3101 0.1144 -0.3207
Hs 578T Tozasertib
0.04
uM
LJP5
 72
hr
 765 841 3148 0.2671 0.0474
Hs 578T Tozasertib
0.12
uM
LJP5
 72
hr
 765 717 3148 0.2280 -0.0309
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 765 768 3148 0.2440 0.0019
Hs 578T Tozasertib
1.11
uM
LJP5
 72
hr
 765 752 3148 0.2389 -0.0091
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 765 770 3148 0.2447 0.0033
Hs 578T Tozasertib
10
uM
LJP5
 72
hr
 765 711 3148 0.2260 -0.0353
Hs 578T Imatinib
0.04
uM
LJP6
 72
hr
 765 3029 3101 0.9768 0.9769
Hs 578T Imatinib
0.12
uM
LJP6
 72
hr
 765 3128 3101 1.0084 1.0082
Hs 578T Imatinib
0.37
uM
LJP6
 72
hr
 765 3138 3101 1.0117 1.0113
Hs 578T Imatinib
1.11
uM
LJP6
 72
hr
 765 3275 3101 1.0558 1.0544
Hs 578T Imatinib
3.33
uM
LJP6
 72
hr
 765 3256 3101 1.0498 1.0487
Hs 578T Imatinib
10
uM
LJP6
 72
hr
 765 3387 3101 1.0920 1.0892
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 765 2879 3101 0.9283 0.9277
Hs 578T NVP-TAE684
0.12
uM
LJP6
 72
hr
 765 1895 3101 0.6112 0.5671
Hs 578T NVP-TAE684
0.37
uM
LJP6
 72
hr
 765 2148 3101 0.6928 0.6677
Hs 578T NVP-TAE684
1.11
uM
LJP6
 72
hr
 765 1479 3101 0.4766 0.3852
Hs 578T NVP-TAE684
3.33
uM
LJP6
 72
hr
 765 891 3101 0.2871 0.0772
Hs 578T NVP-TAE684
10
uM
LJP6
 72
hr
 765 531 3101 0.1713 -0.1669
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 765 2650 3148 0.8417 0.8378