LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
MCF7 | Seliciclib | 0.04 | uM | LJP5 | 72 | hr | 1389 | 5996 | 5905 | 1.0155 | 1.0149 |
MCF7 | Seliciclib | 0.12 | uM | LJP5 | 72 | hr | 1389 | 5970 | 5905 | 1.0109 | 1.0104 |
MCF7 | Seliciclib | 0.37 | uM | LJP5 | 72 | hr | 1389 | 5718 | 5905 | 0.9670 | 0.9662 |
MCF7 | Seliciclib | 1.11 | uM | LJP5 | 72 | hr | 1389 | 5276 | 5905 | 0.8927 | 0.8934 |
MCF7 | Seliciclib | 3.33 | uM | LJP5 | 72 | hr | 1389 | 4844 | 5905 | 0.8197 | 0.8176 |
MCF7 | Seliciclib | 10 | uM | LJP5 | 72 | hr | 1389 | 1278 | 5905 | 0.2160 | -0.0411 |
MCF7 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 5420 | 5445 | 0.9987 | 0.9994 |
MCF7 | AT-7519 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 2530 | 5445 | 0.4655 | 0.3558 |
MCF7 | AT-7519 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 755 | 5445 | 0.1389 | -0.2665 |
MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 553 | 5445 | 0.1017 | -0.3754 |
MCF7 | AT-7519 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 479 | 5445 | 0.0885 | -0.4181 |
MCF7 | AT-7519 | 10 | uM | LJP6 | 72 | hr | 1389 | 344 | 5445 | 0.0635 | -0.5080 |
MCF7 | AZD7762 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 1987 | 5445 | 0.3659 | 0.2000 |
MCF7 | AZD7762 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1691 | 5445 | 0.3110 | 0.1047 |
MCF7 | AZD7762 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1519 | 5445 | 0.2789 | 0.0452 |
MCF7 | AZD7762 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1327 | 5445 | 0.2444 | -0.0227 |
MCF7 | AZD7762 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1098 | 5445 | 0.2015 | -0.1148 |
MCF7 | AZD7762 | 10 | uM | LJP6 | 72 | hr | 1389 | 771 | 5445 | 0.1412 | -0.2608 |
MCF7 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1389 | 1577 | 5445 | 0.2898 | 0.0624 |
MCF7 | AZD8055 | 0.12 | uM | LJP6 | 72 | hr | 1389 | 1399 | 5445 | 0.2563 | -0.0001 |
MCF7 | AZD8055 | 0.37 | uM | LJP6 | 72 | hr | 1389 | 1451 | 5445 | 0.2657 | 0.0181 |
MCF7 | AZD8055 | 1.11 | uM | LJP6 | 72 | hr | 1389 | 1511 | 5445 | 0.2763 | 0.0381 |
MCF7 | AZD8055 | 3.33 | uM | LJP6 | 72 | hr | 1389 | 1413 | 5445 | 0.2590 | 0.0062 |
MCF7 | AZD8055 | 10 | uM | LJP6 | 72 | hr | 1389 | 1120 | 5445 | 0.2052 | -0.1075 |
MCF7 | Sorafenib | 0.04 | uM | LJP6 | 72 | hr | 1389 | 5186 | 5445 | 0.9513 | 0.9475 |