LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
MCF7 Seliciclib
0.04
uM
LJP5
72
hr
1389 5996 5905 1.0155 1.0149
MCF7 Seliciclib
0.12
uM
LJP5
72
hr
1389 5970 5905 1.0109 1.0104
MCF7 Seliciclib
0.37
uM
LJP5
72
hr
1389 5718 5905 0.9670 0.9662
MCF7 Seliciclib
1.11
uM
LJP5
72
hr
1389 5276 5905 0.8927 0.8934
MCF7 Seliciclib
3.33
uM
LJP5
72
hr
1389 4844 5905 0.8197 0.8176
MCF7 Seliciclib
10
uM
LJP5
72
hr
1389 1278 5905 0.2160 -0.0411
MCF7 AT-7519
0.04
uM
LJP6
72
hr
1389 5420 5445 0.9987 0.9994
MCF7 AT-7519
0.12
uM
LJP6
72
hr
1389 2530 5445 0.4655 0.3558
MCF7 AT-7519
0.37
uM
LJP6
72
hr
1389 755 5445 0.1389 -0.2665
MCF7 AT-7519
1.11
uM
LJP6
72
hr
1389 553 5445 0.1017 -0.3754
MCF7 AT-7519
3.33
uM
LJP6
72
hr
1389 479 5445 0.0885 -0.4181
MCF7 AT-7519
10
uM
LJP6
72
hr
1389 344 5445 0.0635 -0.5080
MCF7 AZD7762
0.04
uM
LJP6
72
hr
1389 1987 5445 0.3659 0.2000
MCF7 AZD7762
0.12
uM
LJP6
72
hr
1389 1691 5445 0.3110 0.1047
MCF7 AZD7762
0.37
uM
LJP6
72
hr
1389 1519 5445 0.2789 0.0452
MCF7 AZD7762
1.11
uM
LJP6
72
hr
1389 1327 5445 0.2444 -0.0227
MCF7 AZD7762
3.33
uM
LJP6
72
hr
1389 1098 5445 0.2015 -0.1148
MCF7 AZD7762
10
uM
LJP6
72
hr
1389 771 5445 0.1412 -0.2608
MCF7 AZD8055
0.04
uM
LJP6
72
hr
1389 1577 5445 0.2898 0.0624
MCF7 AZD8055
0.12
uM
LJP6
72
hr
1389 1399 5445 0.2563 -0.0001
MCF7 AZD8055
0.37
uM
LJP6
72
hr
1389 1451 5445 0.2657 0.0181
MCF7 AZD8055
1.11
uM
LJP6
72
hr
1389 1511 5445 0.2763 0.0381
MCF7 AZD8055
3.33
uM
LJP6
72
hr
1389 1413 5445 0.2590 0.0062
MCF7 AZD8055
10
uM
LJP6
72
hr
1389 1120 5445 0.2052 -0.1075
MCF7 Sorafenib
0.04
uM
LJP6
72
hr
1389 5186 5445 0.9513 0.9475
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