LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T CGP60474
0.04
uM
LJP6
 72
hr
 765 346 3101 0.1119 -0.3251
Hs 578T CGP60474
0.12
uM
LJP5
 72
hr
 765 592 3148 0.1883 -0.1177
Hs 578T CGP60474
0.12
uM
LJP6
 72
hr
 765 382 3101 0.1233 -0.2908
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 765 396 3148 0.1260 -0.2754
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 765 422 3101 0.1362 -0.2549
Hs 578T CGP60474
1.11
uM
LJP5
 72
hr
 765 395 3148 0.1257 -0.2762
Hs 578T CGP60474
1.11
uM
LJP6
 72
hr
 765 410 3101 0.1323 -0.2656
Hs 578T CGP60474
3.33
uM
LJP5
 72
hr
 765 376 3148 0.1194 -0.2943
Hs 578T CGP60474
3.33
uM
LJP6
 72
hr
 765 292 3101 0.0943 -0.3810
Hs 578T CGP60474
10
uM
LJP5
 72
hr
 765 428 3148 0.1360 -0.2478
Hs 578T CGP60474
10
uM
LJP6
 72
hr
 765 218 3101 0.0704 -0.4644
Hs 578T PD173074
0.04
uM
LJP6
 72
hr
 765 2421 3101 0.7807 0.7691
Hs 578T PD173074
0.12
uM
LJP6
 72
hr
 765 2313 3101 0.7458 0.7294
Hs 578T PD173074
0.37
uM
LJP6
 72
hr
 765 2368 3101 0.7633 0.7494
Hs 578T PD173074
1.11
uM
LJP6
 72
hr
 765 2441 3101 0.7870 0.7762
Hs 578T PD173074
3.33
uM
LJP6
 72
hr
 765 2334 3101 0.7524 0.7370
Hs 578T PD173074
10
uM
LJP6
 72
hr
 765 828 3101 0.2671 0.0394
Hs 578T Crizotinib
0.04
uM
LJP5
 72
hr
 765 3186 3148 1.0120 1.0117
Hs 578T Crizotinib
0.12
uM
LJP5
 72
hr
 765 3102 3148 0.9854 0.9856
Hs 578T Crizotinib
0.37
uM
LJP5
 72
hr
 765 2868 3148 0.9110 0.9107
Hs 578T Crizotinib
1.11
uM
LJP5
 72
hr
 765 2701 3148 0.8580 0.8547
Hs 578T Crizotinib
3.33
uM
LJP5
 72
hr
 765 1616 3148 0.5135 0.4417
Hs 578T Crizotinib
10
uM
LJP5
 72
hr
 765 662 3148 0.2103 -0.0696
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 765 3082 3101 0.9938 0.9939
Hs 578T BMS345541
0.12
uM
LJP6
 72
hr
 765 3036 3101 0.9787 0.9787