LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Normalized Growth Rate Inhibition Value
Hs 578T Erlotinib
10
uM
LJP5
 72
hr
 765 1776 3148 0.5644 0.5110
Hs 578T Gefitinib
0.04
uM
LJP6
 72
hr
 765 3063 3101 0.9878 0.9878
Hs 578T Gefitinib
0.12
uM
LJP6
 72
hr
 765 3041 3101 0.9806 0.9807
Hs 578T Gefitinib
0.37
uM
LJP6
 72
hr
 765 3018 3101 0.9731 0.9731
Hs 578T Gefitinib
1.11
uM
LJP6
 72
hr
 765 3074 3101 0.9912 0.9913
Hs 578T Gefitinib
3.33
uM
LJP6
 72
hr
 765 3049 3101 0.9832 0.9830
Hs 578T Gefitinib
10
uM
LJP6
 72
hr
 765 2677 3101 0.8631 0.8593
Hs 578T Nilotinib
0.04
uM
LJP5
 72
hr
 765 3536 3148 1.1233 1.1169
Hs 578T Nilotinib
0.12
uM
LJP5
 72
hr
 765 3572 3148 1.1346 1.1276
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 765 3523 3148 1.1192 1.1132
Hs 578T Nilotinib
1.11
uM
LJP5
 72
hr
 765 3401 3148 1.0804 1.0771
Hs 578T Nilotinib
3.33
uM
LJP5
 72
hr
 765 3516 3148 1.1168 1.1109
Hs 578T Nilotinib
10
uM
LJP5
 72
hr
 765 662 3148 0.2105 -0.0684
Hs 578T JNK-9L
0.04
uM
LJP6
 72
hr
 765 3208 3101 1.0342 1.0334
Hs 578T JNK-9L
0.12
uM
LJP6
 72
hr
 765 3104 3101 1.0011 1.0011
Hs 578T JNK-9L
0.37
uM
LJP6
 72
hr
 765 2814 3101 0.9072 0.9057
Hs 578T JNK-9L
1.11
uM
LJP6
 72
hr
 765 1954 3101 0.6300 0.5908
Hs 578T JNK-9L
3.33
uM
LJP6
 72
hr
 765 863 3101 0.2783 0.0613
Hs 578T JNK-9L
10
uM
LJP6
 72
hr
 765 531 3101 0.1713 -0.1659
Hs 578T PD0325901
0.04
uM
LJP5
 72
hr
 765 1689 3148 0.5367 0.4744
Hs 578T PD0325901
0.04
uM
LJP6
 72
hr
 765 1638 3101 0.5285 0.4583
Hs 578T PD0325901
0.12
uM
LJP5
 72
hr
 765 1435 3148 0.4559 0.3611
Hs 578T PD0325901
0.12
uM
LJP6
 72
hr
 765 1399 3101 0.4513 0.3485
Hs 578T PD0325901
0.37
uM
LJP5
 72
hr
 765 1349 3148 0.4285 0.3201
Hs 578T PD0325901
0.37
uM
LJP6
 72
hr
 765 1299 3101 0.4188 0.2993