LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 12 of 15: Mean cell count and mean normalized growth rate inhibition values across biological replicate 2. - Dataset (ID:20249)
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Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | WZ3105 | 3.33 | uM | LJP5 | 72 | hr | 765 | 412 | 3148 | 0.1309 | -0.2617 |
Hs 578T | WZ3105 | 10 | uM | LJP5 | 72 | hr | 765 | 386 | 3148 | 0.1227 | -0.2845 |
Hs 578T | XMD11-50 | 0.04 | uM | LJP6 | 72 | hr | 765 | 3057 | 3101 | 0.9855 | 0.9855 |
Hs 578T | XMD11-50 | 0.12 | uM | LJP6 | 72 | hr | 765 | 2921 | 3101 | 0.9419 | 0.9414 |
Hs 578T | XMD11-50 | 0.37 | uM | LJP6 | 72 | hr | 765 | 2638 | 3101 | 0.8507 | 0.8459 |
Hs 578T | XMD11-50 | 1.11 | uM | LJP6 | 72 | hr | 765 | 2104 | 3101 | 0.6784 | 0.6502 |
Hs 578T | XMD11-50 | 3.33 | uM | LJP6 | 72 | hr | 765 | 1520 | 3101 | 0.4904 | 0.4049 |
Hs 578T | XMD11-50 | 10 | uM | LJP6 | 72 | hr | 765 | 548 | 3101 | 0.1768 | -0.1528 |
Hs 578T | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 765 | 3051 | 3101 | 0.9836 | 0.9836 |
Hs 578T | XMD11-85h | 0.12 | uM | LJP6 | 72 | hr | 765 | 3132 | 3101 | 1.0100 | 1.0099 |
Hs 578T | XMD11-85h | 0.37 | uM | LJP6 | 72 | hr | 765 | 2984 | 3101 | 0.9618 | 0.9616 |
Hs 578T | XMD11-85h | 1.11 | uM | LJP6 | 72 | hr | 765 | 2861 | 3101 | 0.9225 | 0.9217 |
Hs 578T | XMD11-85h | 3.33 | uM | LJP6 | 72 | hr | 765 | 2622 | 3101 | 0.8455 | 0.8405 |
Hs 578T | XMD11-85h | 10 | uM | LJP6 | 72 | hr | 765 | 1235 | 3101 | 0.3981 | 0.2668 |
Hs 578T | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 765 | 1365 | 3148 | 0.4338 | 0.3281 |
Hs 578T | XMD16-144 | 0.12 | uM | LJP5 | 72 | hr | 765 | 828 | 3148 | 0.2630 | 0.0395 |
Hs 578T | XMD16-144 | 0.37 | uM | LJP5 | 72 | hr | 765 | 845 | 3148 | 0.2686 | 0.0503 |
Hs 578T | XMD16-144 | 1.11 | uM | LJP5 | 72 | hr | 765 | 821 | 3148 | 0.2610 | 0.0355 |
Hs 578T | XMD16-144 | 3.33 | uM | LJP5 | 72 | hr | 765 | 676 | 3148 | 0.2147 | -0.0591 |
Hs 578T | XMD16-144 | 10 | uM | LJP5 | 72 | hr | 765 | 361 | 3148 | 0.1147 | -0.3082 |
Hs 578T | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 765 | 3116 | 3148 | 0.9898 | 0.9899 |
Hs 578T | Erlotinib | 0.12 | uM | LJP5 | 72 | hr | 765 | 3110 | 3148 | 0.9879 | 0.9880 |
Hs 578T | Erlotinib | 0.37 | uM | LJP5 | 72 | hr | 765 | 3032 | 3148 | 0.9632 | 0.9635 |
Hs 578T | Erlotinib | 1.11 | uM | LJP5 | 72 | hr | 765 | 2928 | 3148 | 0.9301 | 0.9301 |
Hs 578T | Erlotinib | 3.33 | uM | LJP5 | 72 | hr | 765 | 2852 | 3148 | 0.9059 | 0.9053 |